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20:05, 15 July 2024 Nikolas talk contribs created page A5. Leg ulcer (Created page with "= Leg ulcer = {{#lst:Leg ulcer|dermatology}} = Peripheral artery disease = {{#lst:Peripheral artery disease|dermatology}} = Chronic venous disorder = {{#lst:Chronic venous disorder|dermatology}}") Tag: Visual edit: Switched
19:52, 15 July 2024 Nikolas talk contribs deleted page Blog:Test (content was: "<vote />  This is a test! <comments /> Category:Articles by user Nikolas Category:15 July 2024 __NOEDITSECTION__", and the only contributor was "Nikolas" (talk))
19:51, 15 July 2024 Nikolas talk contribs created page Blog:New.greek.doctor now generates PDFs! (New blog post created.)
18:43, 15 July 2024 Nikolas talk contribs created page Blog:Test (New blog post created.)
09:32, 15 July 2024 Nikolas talk contribs created page Category:Diabetology (POTE course) (Created page with "Category:5th year") Tag: Visual edit
13:36, 10 July 2024 Nikolas talk contribs created page Blood culture (Created page with "'''Blood culture''' is an examination for bacteraemia where blood is sampled and collected in special flasks which contain a medium which provides bacteria and fungi with the resources they need to grow. It's a commonly used examination in the hospital and is indicated when there are signs of invasive bacterial or fungal infection. Because the bacteria are cultured, it's possible to perform antibiotic resistance analysis of any bacteria which are present, which is v...") Tag: Visual edit
12:57, 10 July 2024 Nikolas talk contribs created page Category:Microbiology (Created blank page)
11:32, 8 July 2024 Nikolas talk contribs created page Category:Pharmacology (Created page with "Category:Pages by subject") Tag: Visual edit
10:38, 5 July 2024 Nikolas talk contribs deleted page 53. Dermoid cyst (Duplicate of 38)
10:31, 5 July 2024 Nikolas talk contribs deleted page 10. Rectal adenocarcinoma (Duplicate of 40)
16:50, 27 June 2024 Nikolas talk contribs deleted page 57. Carcinoma of the breast (duplicate of 36)
16:45, 27 June 2024 Nikolas talk contribs deleted page 39. Cerebral atrophy (duplicate of 16)
16:38, 27 June 2024 Nikolas talk contribs deleted page 16. Cholelithiasis, chronic cholecystitis and empyema (content was: "{{:13. Cholelithiasis, chronic cholecystitis and empyema}} Category:Pathology 2 - Macropreparations", and the only contributor was "Nikolas" (talk))
19:58, 26 June 2024 Nikolas talk contribs created page Leg ulcer (Created page with "* Etiology ** Chronic venous disease ** Peripheral artery disease ** Neuropathic ulcer *** Diabetes ** Decubitus ** Trauma ** Infections ** Dermatoses (<abbr>SLE</abbr>, pyoderma gangrenosum) ** Neoplastic * Morphology ** Venous ulcer *** Above the ankle *** Mild pain **** Pain improves when raising leg *** Shallow ulcer ** Arterial ulcer *** Punched-out well-defined ulcer *** Pressure points of the legs (malleolus, toes) *** Severe pain **** Pain worsens when raising le...") Tag: Visual edit: Switched
07:02, 21 June 2024 Nikolas talk contribs created page MediaWiki:Retrievedfrom (Created page with "End of page.")
16:24, 20 June 2024 Nikolas talk contribs created page MediaWiki:Print.css (Created page with "CSS placed here will affect the print output: Infobox template style: .infobox { border: 1px solid #a2a9b1; border-spacing: 3px; background-color: #f8f9fa; color: black; @noflip: margin: 0.5em 0 0.5em 1em; padding: 0.2em; @noflip: float: right; @noflip: clear: right; font-size: 88%; line-height: 1.5em; width: 22em; }")
11:47, 18 June 2024 Nikolas talk contribs created page A4. Atopic dermatitis (Created page with "{{#lst:Atopic dermatitis|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
11:46, 18 June 2024 Nikolas talk contribs created page Atopic dermatitis (Created page with "<section begin="dermatology" />* Affects 10% of children, but only 1 – 3% of adults * Associated with other atopic diseases ** Asthma ** Allergic rhinitis * Etiology ** Polygenic inheritance ** Environmental riggers *** Dust *** Heat *** Infection *** Skin irritation * Pathophysiology ** Epidermal skin barrier defect *** -> water loss *** -> allergens can penetrate barrier ** Abnormal immune response * Clinical features ** Morphology *** Acute **** Erythematous maculop...") Tag: Visual edit: Switched
11:46, 18 June 2024 Nikolas talk contribs created page A3. Basal cell carcinoma and squamous cell carcinoma (Created page with "= Basal cell carcinoma = {{#lst:Basal cell carcinoma|dermatology}} = Squamous cell carcinoma = {{#lst:Squamous cell carcinoma|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
11:44, 18 June 2024 Nikolas talk contribs created page Squamous cell carcinoma (Created page with "<section begin="dermatology" /> * Second most common skin cancer * Risk factors ** Chronic sun exposure ** Precancerous lesions *** Actinic keratosis *** Bowen disease (SCC in situ) *** Leukoplakia ** Radiation ** Chronic scars, ulcers ** Arsenic, tar * Clinical features ** Painless, non-healing, bleeding ulcer or nodule ** Rapid growing ** On sun-exposed areas *** Face and neck *** Lower lip * Prognosis ** 5% risk of metastasis * Diagnosis ** Punch biopsy * Treatment **...") Tag: Visual edit
11:44, 18 June 2024 Nikolas talk contribs created page Basal cell carcinoma (Created page with "<section begin="dermatology" /> * Most common skin cancer * Related to mutations in the hedgehog pathway * Risk factors ** Chronic sun exposure ** Old age ** Skin types I and II * Clinical features ** Pearly papule or nodule ** Rolled border ** Central crater of ulceration ** On sun-exposed skin *** Usually upper lip/nose area ** Slow growing * Types ** Nodular BCC *** Most common type ** Superficial BCC *** On trunk *** Flat plaque lesion ** Nevoid basal cell carcinoma...") Tag: Visual edit
11:42, 18 June 2024 Nikolas talk contribs moved page 2. Pyodermas to A2. Pyodermas
11:42, 18 June 2024 Nikolas talk contribs created page 2. Pyodermas (Created page with "= Impetigo = {{#lst:Impetigo|dermatology}} = Cellulitis = {{#lst:Cellulitis|dermatology}} = Erysipelas = {{#lst:Erysipelas|dermatology}} = Necrotising soft tissue infection = {{#lst:Necrotising soft tissue infection|dermatology}} = Folliculitis = {{#lst:Folliculitis|dermatology}} = Furuncle and carbuncle = {{#lst:Furuncle and carbuncle|dermatology}} = Skin abscess = * Large nodule") Tag: Visual edit: Switched
11:40, 18 June 2024 Nikolas talk contribs created page Furuncle and carbuncle (Created page with "<section begin="dermatology" />* Furuncle ** Well-demarcated, firm, painful, purulent nodule ** Large red base ** Subcutaneous abscess * Carbuncle ** Coalescence of furuncles <section end="dermatology" /> Category:Dermatology") Tag: Visual edit: Switched
11:39, 18 June 2024 Nikolas talk contribs created page Folliculitis (Created page with "<section begin="dermatology" />* Inflammation of follicle * Any age group * Terminal or vellus hairs * Usually bacterial ** Mainly staph aureus * Clinical features ** Tender papule/pustule of hair follicle * Treatment ** Dicloxacillin ** Incision and drainage for large lesions <section end="dermatology" /> Category:Dermatology") Tag: Visual edit: Switched
11:37, 18 June 2024 Nikolas talk contribs created page Erysipelas (Created page with "<section begin="dermatology" />* Special type of cellulitis caused by strep pyogenes * Epidemiology ** Children ** Poor circulation *** Stasis ** Diabetics ** Chronic oedema * Spreads by superficial lymph vessels * Clinical features ** On lower limbs – 80% ** On face – rarely ** Large erythema, irregular borders ** Tender ** Rapidly advancing borders ** Oedema ** Warm ** Fever * Site of entry needs to be located ** Ulcers ** Interdigital lesion ** Fungal infections *...") Tag: Visual edit: Switched
11:34, 18 June 2024 Nikolas talk contribs created page Cellulitis (Created page with "<section begin="dermatology" />* Deeper than impetigo * Infection of deep dermis and subcutaneous tissue * Etiology ** Staph aureus -> purulent cellulitis ** Strep pyogenes -> nonpurulent cellulitis * Primary – entry through minor skin injury * Secondary – to systemic infection * Clinical features ** Erythematous lesion with poorly defined margins ** Purulent cellulitis -> purulent exudate * Treatment ** Cloxacillin <section end="dermatology" /> Category:Dermatolog...") Tag: Visual edit: Switched
11:32, 18 June 2024 Nikolas talk contribs created page Impetigo (Created page with "<section begin="dermatology" />* Superficial skin infection * Highly infectious * Children ** Most common bacterial skin infection in children * Etiology ** Staph aureus – 80% ** Strep pyogenes ** Risk factors *** Diabetes *** Immunosuppression ** Secondary – superinfection of atopic dermatitis, etc * Clinical features ** Honey-crusted lesions *** The result of ruptured pustules ** Central face ** Itching ** Can be bullous * Types ** Ecthyma *** A form of impetigo th...") Tag: Visual edit: Switched
11:30, 18 June 2024 Nikolas talk contribs created page Category:Dermatology (Created blank page) Tag: Visual edit
11:30, 18 June 2024 Nikolas talk contribs created page Category:Dermatology (POTE course) (Created page with "Category:4th year") Tag: Visual edit
11:30, 18 June 2024 Nikolas talk contribs created page A1. Psoriasis (Created page with "{{#lst:Psoriasis|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
11:27, 18 June 2024 Nikolas talk contribs created page Psoriasis (Created page with "* A type of systemic papulosquamous dijusease * Epidemiology ** 2% of whites, less common in other skin colours ** 20 – 40 years *** Family history ** 50 – 100 years *** No family history * Etiology ** Polygenic inheritance (HLA) ** Triggers *** Streptococci <abbr>URTI</abbr> *** Irritation of skin *** Staph *** HIV *** Mechanical irritation *** Alcohol *** Stress *** Drugs **** Beta blockers **** Lithium **** Interferon **** Chloroquine * Pathophysiology ** Acanthos...") Tag: Visual edit
11:09, 18 June 2024 Nikolas talk contribs created page 51. Toxicology tests in the clinical laboratory (Created page with "* Methods ** High performance liquid chromatography *** Can detect many drugs at the same time ** Immunoassay ** Alcohol -> enzymatic reaction + UV detection, gas chromatography * In blood or urine * Mostly qualitative, sometimes quantitative * Often checked drugs ** Benzos ** Barbs ** Illegal drugs ** Alcohol * Indications ** Suspected poisoning ** Unexplainable sickness Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
11:07, 18 June 2024 Nikolas talk contribs created page 50. Therapeutic drug monitoring (TDM) (Created page with "{{#lst:Therapeutic drug monitoring|clinical biochemistry}}")
11:06, 18 June 2024 Nikolas talk contribs created page Therapeutic drug monitoring (Created page with "{{:Stub}} = measurement of drug concentration or activity in plasma * Methods ** High performance liquid chromatography ** Immunoassay * Indications ** Non-linear kinetics of drug ** When there is poor compliance ** If the therapeutic effect can’t be assessed clinically ** If the therapeutic index is low *** Warfarin *** Aminoglycosides *** Antipsychotics *** Digoxin *** Lithium ** When there are signs of overdose ** To determine pharmacokinetic interactions Categ...") Tag: Visual edit
11:04, 18 June 2024 Nikolas talk contribs created page 49. Molecular biology applications in the practice of clinical laboratories (Created page with "Molecular biology methods * High sensitivity and specificity * Expensive * Real-time PCR ** Visualization – fluorescent dyes, hybridization * DNA sequencing ** Next generation sequencing ** Whole exome sequencing * Benefit * Diagnosis ** Prognosis ** Therapy response * Monogenic disorders ** Sickle cell anaemia ** Thalassaemia * Microbiological assays ** HepC ** HepB ** CMV ** <abbr>EBV</abbr> ** HSV ** Gonorrhoea * Inherited conditions ** Factor V Leiden ** Prothr...") Tag: Visual edit
11:02, 18 June 2024 Nikolas talk contribs created page 48. Tumor markers and their informational value in the clinical laboratory practice (Created page with "{{#lst:Tumour marker|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
10:55, 18 June 2024 Nikolas talk contribs created page Afp (Redirected page to Tumour marker#Alpha-foetoprotein) Tags: New redirect Visual edit
10:52, 18 June 2024 Nikolas talk contribs created page PSA (Redirected page to Tumour marker#Prostate specific antigen) Tags: New redirect Visual edit
10:52, 18 June 2024 Nikolas talk contribs created page Prostate specific antigen (Redirected page to Tumour marker#Prostate specific antigen) Tags: New redirect Visual edit
10:51, 18 June 2024 Nikolas talk contribs created page Tumour marker (Created page with "<section begin="pathology" />A '''tumour marker''', also called a '''cancer biomarker''', is a substance found in the body which concentration in the blood or other body fluid increases when cancer is present. The tumour marker may be produced by the cancer cells themselves or by healthy cells in response to the cancer. Tumour markers are usually proteins and are often produced in small amounts even in people without cancer. The term tumour marker may also be used to...") Tag: Visual edit: Switched
10:27, 18 June 2024 Nikolas talk contribs created page Cancer treatment (Redirected page to Cancer therapy) Tags: New redirect Visual edit
10:13, 18 June 2024 Nikolas talk contribs created page 47. The most important non-specific laboratory tests that suggest the presence of malignant diseases. (Created page with "* In any cancer ** Elevated CRP or ESR (without infection or other explanatory cause) * Multiple myeloma ** Extremely high ESR * GI cancer ** Chronic microcytic anaemia * Leukaemias ** Leukocytosis ** Anaemia ** Thrombocytopaenia ** Blasts in bone marrow or blood ** Abnormal differentiation * Bone tumors ** ALP increase * Lung cancer ** LDH increase * Bile duct cancer ** Bilirubin increase * Neuroendocrine tumors ** Hormones * During chemo ** Bone marrow depression ** LD...") Tag: Visual edit
10:09, 18 June 2024 Nikolas talk contribs created page 46. Clinical biochemistry of the disorders of the human reproductive system (Created page with "= Assessment of ovarian reserve = {{#lst:Infertility (female)|clinical biochemistry}} = Polycystic ovary syndrome = {{#lst:Polycystic ovary syndrome|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
10:05, 18 June 2024 Nikolas talk contribs created page Infertility (female) (Created page with "'''Female''' '''infertility''' is defined as the inability of a couple to conceive with regular intercourse without use of contraception after 12 months in women less then 35 years of age, and after 6 months in women 35 years and older. We can distinguish primary and secondary infertility. In primary, the woman has never achieved pregnancy, while in secondary, there’s been at least one previous pregnancy. Fecundability is also relevant. It’s the probability of achi...") Tag: Visual edit
15:32, 30 May 2024 Nikolas talk contribs created page PCOS (Redirected page to Polycystic ovary syndrome) Tags: New redirect Visual edit
15:23, 30 May 2024 Nikolas talk contribs created page Polycystic ovary syndrome (Created page with "<section begin="clinical biochemistry" />'''Polycystic ovary syndrome''' (PCOS) is characterised by oligomenorrhoea, hyperandrogenism, and anovulation. It’s a common disorder, as it affects approx. 10% of women. It’s the most common cause of hyperandrogenism in females. Symptoms usually begin in adolescence.<section end="clinical biochemistry" /> == Risk factors == * Obesity * Diabetes mellitus * Family history == Pathomechanism == The pathomechanism is unknown. O...") Tag: Visual edit
15:16, 30 May 2024 Nikolas talk contribs created page 45. Clinical biochemistry of the disorders of adrenal medulla/cortex (Created page with "* Adrenal cortex ** Hypofunction *** Hyponatraemia *** Hyperkalaemia *** Metabolic acidosis *** Addison disease **** Low cortisol **** ACTH high **** ACTH stimulation -> cortisol remains low (usually rises) *** Secondary/tertiary adrenal insufficiency **** Low cortisol **** ACTH low **** ACTH stimulation -> cortisol increases *** Congenital adrenal hyperplasia **** High levels of 17-hydroxyprogesterone ** Hyperfunction *** Hypernatraemia *** Hypokalaemia *** Metabolic al...") Tag: Visual edit
15:16, 30 May 2024 Nikolas talk contribs created page 44. Laboratory assessment of the thyroid function (Created page with "= Hypothyroidism = {{#lst:Hypothyroidism|clinical biochemistry}} = Hyperthyroidism and thyrotoxicosis= {{#lst:Hyperthyroidism and thyrotoxicosis|clinical biochemistry}} = Hashimoto thyroiditis = {{#lst:Hashimoto thyroiditis|clinical biochemistry}} = Other stuff = * Drugs which affect thyroid function ** Lithium – decreases thyroid hormone release ** Amiodarone – hypo or hyperthyroidism ** SSRIs – increase TSH Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
14:58, 30 May 2024 Nikolas talk contribs created page 43. Clinical biochemistry of the hypothalamus, hypophysis (Created page with "* Dynamic function test ** Administer insulin -> measure cortisol, GH ** Administer GnRH -> measure FSH, LH ** Administer TRH -> measure TSH * GH excess ** Administer oral glucose -> GH still high (usually decreases) * GH deficiency ** Low levels of <abbr>IGF</abbr>-1 ** Administer GHRH -> GH still low (usually increases) * Hyperprolactinaemia ** Serum prolactin ** Administer dopamine agonist -> prolactin still high (usually decreases) * Diabetes insipidus ** Water depri...") Tag: Visual edit