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17:50, 17 July 2024 Nikolas talk contribs created page A20. Precancerous lesions and intraepidermal carcinoma (Created page with "* Precancerous lesions ** Lentigo maligna ** Actinic keratosis *** Cutaneous horns ** Leucoplakia * Intraepidermal carcinoma/carcinoma in situ ** Bowen disease ** Erythroplasia of Queyrat ** Paget disease = Lentigo maligna = {{#lst:Lentigo maligna|dermatology}} = Actinic keratosis = {{#lst:Actinic keratosis|dermatology}} = Leucoplakia = {{#lst:Leucoplakia|dermatology}} = Bowen disease = {{#lst:Bowen disease|dermatology}} = Erythroplasia of Queyrat = {{#lst:Erythroplasia...") Tag: Visual edit
17:48, 17 July 2024 Nikolas talk contribs created page Paget disease of the breast (Created page with "<section begin="dermatology" />* Ductal carcinoma in situ of the nipple and areola * Clinical features ** Erythematous, scaly, vesicular rash ** Pruritus ** Burning * Treatment ** Surgical removal<section end="dermatology" /> Category:Gynaecology") Tag: Visual edit: Switched
17:47, 17 July 2024 Nikolas talk contribs created page Erythroplasia of Queyrat (Created page with "<section begin="dermatology" />* Erythroplasia of Queyrat = Bowen disease of glans penis * Squamous cell carcinoma in situ of penile mucosa * Risk factors ** Chronic inflammation ** HPV 16, 18 * Clinical features ** Sharply demarcated, non-healing plaques or papules ** May ulcerate or bleed * Treatment ** 5-FU ** Imiquimod<section end="dermatology" /> Category:Dermatology Category:Urology") Tag: Visual edit: Switched
17:46, 17 July 2024 Nikolas talk contribs created page Bowen disease (Created page with "<section begin="dermatology" />* Squamous cell carcinoma in situ of skin * Risk factors ** UV exposure ** HPV 16, 18 ** Arsenic * Clinical features ** Erythematous and scaly lesion ** Irregular shape, sharp borders ** On sun-exposed areas * Treatment ** 5-FU ** Imiquimod<section end="dermatology" /> Category:Dermatology") Tag: Visual edit: Switched
17:46, 17 July 2024 Nikolas talk contribs created page Leucoplakia (Created page with "<section begin="dermatology" />* Hyperkeratosis and dysplasia of epithelium and mucous membranes * Risk factors ** Smoking ** Alcohol * Clinical features ** White plaque that cannot be scraped off ** Most commonly in oral cavity * Differential diagnosis ** Oral candidiasis ** Oral hairy leukoplakia * Treatment ** Avoidance of risk factors ** Cryotherapy<section end="dermatology" /> Category:Dermatology") Tag: Visual edit
17:45, 17 July 2024 Nikolas talk contribs created page Actinic keratosis (Created page with "<section begin="dermatology" />* Precancerous lesions of squamous cells * Occurs in elderly with light skin * Risk factor: UV exposure * Clinical features ** Small lesion with rough surface ** -> lesion grows and becomes erythematous and scaly ** On sun-exposed areas ** May develop into a cutaneous horn * Treatment ** Few lesions *** Cryotherapy ** Many lesions *** 5-FU *** Imiquimod ** Prevention with sunscreen<section end="dermatology" /> Category:Dermatology") Tag: Visual edit
17:44, 17 July 2024 Nikolas talk contribs created page Lentigo maligna (Created page with "<section begin="dermatology" />* Precancerous lesion of dysplastic melanocytes * Occurs in elderly * Risk factor: UV exposure * Darkly pigmented macule ** On sun-exposed areas *** Face, neck ** Irregular borders ** 1 mm – 2 cm ** Irregular colour * Treatment ** Surgical excision with safety margin<section end="dermatology" /> Category:Dermatology") Tag: Visual edit: Switched
17:43, 17 July 2024 Nikolas talk contribs created page A19. Contact dermatitis (Created page with "{{#lst:Contact dermatitis|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
17:42, 17 July 2024 Nikolas talk contribs created page Contact dermatitis (Created page with "<section begin="dermatology" />* Contact dermatitis ** Types *** Important types **** Allergic contact dermatitis **** Irritant contact dermatitis **** Phototoxic contact dermatitis **** Photoallergic contact dermatitis *** Not so important types **** Seborrheic dermatitis **** Infectallergic dermatitis **** Perioral dermatitis **** Stasis dermatitis ** Clinical features (rash) *** Acute **** “Sunburn type” ***** Erythema ***** Oedema ***** Vesicles ***** Urtica ****...") Tag: Visual edit: Switched
17:41, 17 July 2024 Nikolas talk contribs created page A18. Vasculitides (Created page with "= Cutaneous small vessel vasculitis = {{#lst:Cutaneous small vessel vasculitis|dermatology}} = Cryoglobulinaemic vasculitis = {{#lst:Cryoglobulinaemic vasculitis|dermatology}} = IgA vasculitis = {{#lst:IgA vasculitis|dermatology}} = Urticarial vasculitis = {{#lst:Urticarial vasculitis|dermatology}} = Granulomatosis with polyangiitis = {{#lst:Granulomatosis with polyangiitis|dermatology}} = Eosinophilic granulomatosis with polyangiitis = {{#lst:Eosinophilic granulomatosis...") Tag: Visual edit
17:38, 17 July 2024 Nikolas talk contribs created page Polyarteritis nodosa (Created page with "<section begin="dermatology" />* Medium-sized vessel vasculitis * Clinical features ** Skin symptoms (in 25%) *** Palpable purpuras *** Punched-out ulcers ** Coronary artery disease ** Renal disease ** Polyneuropathy * Treatment ** Steroids ** Immunosuppressants<section end="dermatology" /> Category:Rheumatology") Tag: Visual edit: Switched
17:37, 17 July 2024 Nikolas talk contribs created page Eosinophilic granulomatosis with polyangiitis (Created page with "<section begin="dermatology" />* Clinical features ** Skin symptoms (in 50%) *** Nodules *** Palpable purpuras ** Severe asthma ** Allergic rhinitis ** Respiratory tract infections * Treatment ** Steroids ** Immunosuppressants<section end="dermatology" /> Category:Rheumatology") Tag: Visual edit: Switched
17:37, 17 July 2024 Nikolas talk contribs created page Granulomatosis with polyangiitis (Created page with "<section begin="dermatology" />* Potentially lethal * Clinical features ** Skin symptoms (in 50%) *** Papules *** Purpuras *** Oral ulcers ** Chronic rhinosinusitis ** Lower respiratory tract infections ** Glomerulonephritis * Treatment ** Steroids ** Immunosuppressants<section end="dermatology" /> Category:Rheumatology") Tag: Visual edit: Switched
17:36, 17 July 2024 Nikolas talk contribs created page Urticarial vasculitis (Created page with "<section begin="dermatology" />* Persistent urticaria * Associated with autoimmune connective tissue diseases * Can be due to hypocomplementemia (deficiency of complement factors) ** In which case there is also systemic involvement * Clinical features ** Recurrent episodes of painful, persistent urticarial lesions that last > 24 hours ** Angioedema can occur * Treatment ** Antihistamines ** Steroids ** NSAIDs ** Dapsone<section end="dermatology" /> Category:Dermatolog...") Tag: Visual edit: Switched
17:36, 17 July 2024 Nikolas talk contribs created page Cryoglobulinaemic vasculitis (Created page with "<section begin="dermatology" />* Cryoglobulins = immunoglobulins that precipitate in the cold ** They precipitate within the walls of small vessels * Etiology ** Viral infections ** Autoimmune connective tissue diseases ** Haematological malignancies * Clinical features ** Palpable purpura (in 90%) ** Myalgia ** Arthralgia ** Peripheral neuropathy ** Glomerulonephritis * Diagnosis ** Examination of cryoglobulins in blood during attack * Treatment ** Treat underlying dise...") Tag: Visual edit: Switched
17:35, 17 July 2024 Nikolas talk contribs created page IgA vasculitis (Created page with "<section begin="dermatology" />* IgA deposit in the vessels * Typically affect children after a respiratory tract infection * Clinical features (typical tetrad) ** Palpable purpura (in 100%) ** Arthritis ** Abdominal pain ** Haematuria * Treatment ** Self-limiting in most cases – no treatment needed ** NSAIDs ** Steroids if severe<section end="dermatology" /> Category:Rheumatology Category:Paediatrics") Tag: Visual edit: Switched
17:33, 17 July 2024 Nikolas talk contribs created page Cutaneous small vessel vasculitis (Created page with "<section begin="dermatology" />* Small vessel vasculitides with cutaneous involvement * Most cases are idiopathic * Types ** Immune complex mediated vasculitides *** Cryoglobulinaemic vasculitis *** <abbr>IgA</abbr> vasculitis = Henoch Schönlein purpura *** Urticarial vasculitis ** ANCA-associated vasculitides *** Granulomatosis with polyangiitis *** Eosinophilic granulomatosis with polyangiitis * Common clinical features ** Palpable purpuras ** Erythematous papules **...") Tag: Visual edit: Switched
17:25, 17 July 2024 Nikolas talk contribs created page A17. Pigmented naevi (Created page with "{{#lst:Naevus|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
17:24, 17 July 2024 Nikolas talk contribs created page Naevus (Created page with "<section begin="dermatology" />* A nevus is a benign lesion of melanocytes in the skin or oral mucosa * Can be pigmented or non-pigmented (most are pigmented) * Histological classification ** Junctional nevi *** Flat, well-demarcated brown macules *** Grows in the epidermis at the dermal-epidermal junction ** Compound nevi *** Elevated *** Grows in the epidermis at the dermal-epidermal junction and in the dermis ** Dermal nevi *** Elevated *** May be hard and grow hair *...") Tag: Visual edit: Switched
17:22, 17 July 2024 Nikolas talk contribs created page A16. Scabies, pediculosis (Created page with "= Scabies = {{#lst:Scabies|dermatology}} = Pediculosis = {{#lst:Pediculosis|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
17:21, 17 July 2024 Nikolas talk contribs created page Pediculosis (Created page with "<section begin="dermatology" />* Lice infection * Transmission by direct physical contact or indirect contact with infected clothes, etc. * Risk factors ** Crowded places ** School ** Homeless * Pathomechanism ** Delayed allergic reaction to lice saliva ** May be asymptomatic for weeks while sensitization occurs * Pediculosis capitis ** Pediculus humanus capitis (head louse) ** Most common in children ** Clinical features *** Scalp/neck pruritus *** Louse eczema on back...") Tag: Visual edit: Switched
17:20, 17 July 2024 Nikolas talk contribs created page Scabies (Created page with "<section begin="dermatology" />* Sarcoptes scabiei var hominis ** Obligate human parasite * Transmission by direct physical contact or contact with infected clothes * Highly contagious * Incubation period 3 – 6 weeks * Risk factors ** Nursing homes ** Childcare facilities ** Prisons * Pathomechanism ** Female mites burrow into stratum corneum, lays eggs and feces ** Feces and dead mites trigger type IV hypersensitivity * Clinical features ** Intense pruritus, especiall...") Tag: Visual edit: Switched
17:19, 17 July 2024 Nikolas talk contribs created page A15. Urticaria (Created page with "{{#lst:Urticaria|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
17:19, 17 July 2024 Nikolas talk contribs created page Urticaria (Created page with "<section begin="dermatology" />* Also called hives * Etiology ** Basically anything, but often idiopathic ** Physical urticaria *** Most common *** Pressure *** Dermatographic urticaria *** Elevated/decreased body temperature *** Sweating *** Sun-exposure ** Allergic urticaria *** Foods **** Fish **** Shellfish **** Nuts **** Eggs *** Drugs **** Penicillin **** Aspirin **** ACE inhibitors **** NSAIDs *** Inhalants ** Autoimmune urticaria ** Vasculitic urticaria ** Infect...") Tag: Visual edit: Switched
17:18, 17 July 2024 Nikolas talk contribs created page A14. Drug allergy (Created page with "= Drug allergy = {{#lst:Drug allergy|dermatology}} = Severe cutaneous adverse reactions = {{#lst:Severe cutaneous adverse reactions|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
17:17, 17 July 2024 Nikolas talk contribs created page Severe cutaneous adverse reactions (Created page with "<section begin="dermatology" />* DRESS syndrome ** Drug-related eosinophilia and systemic symptoms *** Also called drug-induced hypersensitivity syndrome ** Drugs *** Allopurinol *** Antiepileptics *** Antibiotics ** Risk factors *** Older age *** Renal failure *** Certain HLA alleles ** Clinical features *** Fever *** Pruritic morbilliform rash *** Facial oedema ** Multiorgan failure can occur ** Fatal in 10% ** Treatment *** Drug cessation *** Steroids * Toxic epiderma...") Tag: Visual edit: Switched
17:16, 17 July 2024 Nikolas talk contribs deleted page DRESS syndrome (content was: "<section begin="dermatology" />* DRESS = Drug-related eosinophilia and systemic symptoms ** Also called drug-induced hypersensitivity syndrome * Drugs ** Allopurinol ** Antiepileptics ** Antibiotics * Risk factors ** Older age ** Renal failure ** Certain HLA alleles * Clinical features ** Fever ** Pruritic morbilliform rash ** Facial oedema * Multiorgan failure can occur * Fat...", and the only contributor was "Nikolas" (talk))
17:13, 17 July 2024 Nikolas talk contribs created page DRESS syndrome (Created page with "<section begin="dermatology" />* DRESS = Drug-related eosinophilia and systemic symptoms ** Also called drug-induced hypersensitivity syndrome * Drugs ** Allopurinol ** Antiepileptics ** Antibiotics * Risk factors ** Older age ** Renal failure ** Certain HLA alleles * Clinical features ** Fever ** Pruritic morbilliform rash ** Facial oedema * Multiorgan failure can occur * Fatal in 10% * Treatment ** Drug cessation ** Steroids<section end="dermatology" /> Category:Der...") Tag: Visual edit: Switched
17:12, 17 July 2024 Nikolas talk contribs created page Drug allergy (Created page with "<section begin="dermatology" />* Classification according to timeline ** Immediate (< 1 hour) *** Urticaria *** Angioedema *** Rhinitis *** Bronchospasm *** Anaphylaxis ** Non-immediate (> 1 hour) *** Delayed urticaria *** Maculopapular exanthema *** Erythroderma *** Vasculitis *** Stevens-Johnson syndrome (SJS) *** Toxic epidermal necrolysis (TEN) *** Drug reaction with eosinophilia and systemic symptoms (DRESS) *** Acute generalized exanthematous pustulosis (AGEP) ***...") Tag: Visual edit: Switched
17:08, 17 July 2024 Nikolas talk contribs created page A13. Fungal diseases of the skin and its appendages (Created page with "{{#lst:Fungal diseases of the skin and its appendages|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
17:07, 17 July 2024 Nikolas talk contribs created page Fungal diseases of the skin and its appendages (Created page with "<section begin="dermatology" />* Diagnosis of fungal infections ** KOH preparation -> hyphae/yeasts visible under microscope *** KOH dissolves keratin ** Culture ** Wood-light – green fluorescence UV lamp * Treatment of fungal infections ** Terbinafine – for dermatophytoses ** Fluconasol – for candida ** Itraconazole – for candida, dermatophytoses ** Ketoconazole – for Malassezia (pityrasis versicolor) * Epidermomycoses ** By dermatophytes ** Risk factors *** C...") Tag: Visual edit: Switched
17:06, 17 July 2024 Nikolas talk contribs created page A12. Malignant melanoma (Created page with "{{#lst:Melanoma|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
17:03, 17 July 2024 Nikolas talk contribs created page Melanoma (Created page with "<section begin="dermatology" />* Epidemiology ** Only 2% of skin cancer ** Responsible for most skin cancer-related deaths ** Higher incidence in sun-rich countries like Australia compared to Europe ** Average age at onset ~50 * Risk factors ** Excessive UV exposure ** Fitzpatrick skin type I and II *** Easily burns *** Almost never suntans *** Often have freckles ** Precancerous lesions *** Dysplastic nevi *** Dysplastic nevus syndrome – 100% risk of developing melano...") Tag: Visual edit: Switched
17:02, 17 July 2024 Nikolas talk contribs created page A11. Scleroderma and its variants (Created page with "{{#lst:Scleroderma|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
17:01, 17 July 2024 Nikolas talk contribs created page Scleroderma (Created page with "<section begin="dermatology" />* Scleroderma = Abnormal growth of connective tissue * In all types the skin is thickened and hardened * Classification of scleroderma ** Systemic sclerosis/systemic scleroderma *** Limited systemic sclerosis/CREST syndrome *** Diffuse systemic sclerosis *** Systemic sclerosis sine scleroderma ** Localized scleroderma *** Morphea *** Linear scleroderma * Systemic sclerosis ** Sclerosis of internal organs in addition to the skin ** Skin symp...") Tag: Visual edit: Switched
16:59, 17 July 2024 Nikolas talk contribs created page A10. Lupus erythematosus and its variants (Created page with "= Systemic lupus erythematosus = {{#lst:Sle|dermatology}} = Cutaneous lupus erythematosus = {{#lst:Cutaneous lupus erythematosus|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
16:56, 17 July 2024 Nikolas talk contribs created page Sle (Redirected page to Systemic lupus erythematosus) Tags: New redirect Visual edit
16:56, 17 July 2024 Nikolas talk contribs created page Cutaneous lupus erythematosus (Created page with "<section begin="dermatology" />* Chronic discoid lupus erythematosus (CDLE) ** Epidemiology *** Most common cutaneous type *** African American women ** Clinical features *** Erythematous scaling plaques *** -> leaves atrophic scars *** Ocular and mucosal lesions *** Affects face, scalp, neck (sun-exposed areas) *** No systemic symptoms * Subacute cutaneous lupus erythematosus (SCLE) ** Clinical features *** Persisting diffuse erythema on face or sun-exposed areas *** An...") Tag: Visual edit: Switched
16:54, 17 July 2024 Nikolas talk contribs created page A9. Autoimmune bullous skin diseases (Created page with "= Bullous pemphigoid = {{#lst:Bullous pemphigoid|dermatology}} = Pemphigus vulgaris = {{#lst:Pemphigus vulgaris|dermatology}} = Dermatitis herpetiformis = {{#lst:Dermatitis herpetiformis|dermatology}} = Epidermolysis bullosa = {{#lst:Epidermolysis bullosa|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
16:52, 17 July 2024 Nikolas talk contribs created page Epidermolysis bullosa (Created page with "<section begin="dermatology" />* Group of disorders where subepidermal blisters form following trauma * Not autoimmune * Epidermolysis bullosa simplex * Junctional epidermolysis bullosa * Dystrophic epidermolysis bullosa * Epidermolysis bullosa acquisita<section end="dermatology" /> Category:Dermatology") Tag: Visual edit
16:52, 17 July 2024 Nikolas talk contribs created page Dermatitis herpetiformis (Created page with "<section begin="dermatology" />* In young adults * Risk factors ** Coeliac disease ** Iodide sensitivity ** HLA-DR3 ** HLA-DQ2 * Pathomechanism ** Tissue transglutaminase and epidermal transglutaminase antibodies * Clinical features ** Chronic, recurrent ** Tense, grouped, subepidermal vesicles *** Herpetiform appearance, hence the name ** Intensely pruritic ** Bilateral, symmetrical distribution *** Elbows, knees ** No mucosal involvement * Diagnosis ** Coeliac antibodi...") Tag: Visual edit: Switched
16:51, 17 July 2024 Nikolas talk contribs created page Pemphigus vulgaris (Created page with "<section begin="dermatology" />* In middle-aged, elderly * Deadly without treatment * Pathomechanism ** Autoantibodies against desmosomes ** Acantholysis – loss of cell-cell adhesion * Clinical features ** Painful, flaccid, intraepidermal (superficial) blisters ** -> lesions rupture ** -> erosions and crusts ** -> re-epithelialization with hyperpigmentation but no scarring ** No pruritus ** Lesions often begin in oral mucosa then to body parts exposed to pressure * Dia...") Tag: Visual edit
16:51, 17 July 2024 Nikolas talk contribs created page Bullous pemphigoid (Created page with "<section begin="dermatology" />* In elderly * Benign disease, responds well to treatment * Most common autoimmune bullous disease * Pathomechanism ** Autoantibodies against hemidesmosomes * Clinical features ** Prodromal stage *** Weeks before onset of blistering *** Urticarial lesions ** Large, tense, subepidermal bulla *** Don’t rupture easily ** Intensely pruritic ** Lower limbs, axilla ** Rarely oral involvement * Diagnosis ** Negative Nikolsky ** Histology and imm...") Tag: Visual edit: Switched
16:50, 17 July 2024 Nikolas talk contribs created page A8. Skin diseases caused by varicella zoster virus (Created page with "= Varicella = {{#lst:Varicella|dermatology}} = Shingles = {{#lst:Herpes zoster|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
16:48, 17 July 2024 Nikolas talk contribs created page Herpes zoster (Created page with "<section begin="dermatology" />* Shingles (herpes zoster) ** Reactivation ** Older patients ** Triggers *** Immunosuppression *** Advanced age *** Malignancy *** Malnutrition ** Clinical features *** Erupts in dermatome pattern *** Severe pain *** Erythematous maculopapular rash -> vesicles -> rupture ** Complications *** Herpes zoster oticus **** Herpes in facial and vestibulocochlear nerve **** Blindness *** Herpes zoster ophthalmicus **** Herpes in ophthalmic part of...") Tag: Visual edit
16:47, 17 July 2024 Nikolas talk contribs created page Varicella (Created page with " * Varicella (chickenpox) ** Primary infection during childhood ** Lasts 6 days in immunocompetent persons ** Transmission *** Highly contagious *** Airborne transmission *** Incubation period 2 weeks ** Clinical features *** Lesions covering the entire body *** Severe pruritus *** Macules -> papules -> vesicles with erythematous base -> crusts **** All of these stages are present simultaneously, which is a hallmark for the disease *** Fever ** Virus remains latent in se...") Tag: Visual edit: Switched
20:11, 15 July 2024 Nikolas talk contribs created page A7. Herpes simplex virus (HSV) infections of the skin (Created page with "{{#lst:Herpes simplex virus infection|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
20:10, 15 July 2024 Nikolas talk contribs created page Herpes simplex virus infection (Created page with "{{:Stub}} <section begin="dermatology" />* Herpes viruses ** α herpes viruses *** Lie latent in sensory ganglia neurons *** Replicate quickly *** Herpes simplex 1 *** Herpes simplex 2 *** Varicella zoster virus ** β herpes viruses *** Lie latent in leukocytes *** Human herpes virus 6 – roseola infantum/sixth disease *** Human herpes virus 7 *** CMV ** γ herpes viruses *** Lie latent in lymphocytes *** Human herpes virus 8 *** <abbr>EBV</abbr> *** Are oncogenic * HS...") Tag: Visual edit: Switched
20:08, 15 July 2024 Nikolas talk contribs created page A6. Skin diseases caused by human papilloma virus (HPV) (Created page with "{{#lst:Human papilloma virus infection|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
20:08, 15 July 2024 Nikolas talk contribs created page Human papilloma virus infection (Created page with "{{:Stub}} <section begin="dermatology" />* Warts (verruca) ** Histology *** Hyperkeratosis (hyperplasia of str. corneum) *** Acanthosis (hyperplasia of epidermis) *** Papillomatosis ** Hard papules/plaques ** Risk factors *** Immunosuppression ** Due to HPV ** Verruca vulgaris (common wart) *** HPV 1, 2, 4, 7 *** Most common in kids *** On elbows, knees, fingers, palms *** Skin-coloured or whitish, rough, scaly papules *** Cauliflower-appearance ** Verruca plana (flat w...") Tag: Visual edit: Switched