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19:28, 28 July 2024 Nikolas talk contribs deleted redirect Pancreatic cancer by overwriting (Deleted to make way for move from "Pancreatic adenocarcinoma")
16:22, 28 July 2024 Nikolas talk contribs created page 16. Cancer of the oesophagus and the stomach (Created page with "= Oesophageal cancer = {{#lst:Oesophageal cancer|oncology}} = Gastric cancer = {{#lst:Gastric cancer|oncology}} Category:Oncology (POTE course)") Tag: Visual edit
15:46, 28 July 2024 Nikolas talk contribs created page 15. Breast Cancer (Created page with "{{#lst:Breast cancer|oncology}}") Tag: Visual edit
14:14, 28 July 2024 Nikolas talk contribs created page 14. Lung cancer (Created page with "{{#lst:Lung cancer|oncology}} Category:Oncology (POTE course)") Tag: Visual edit
13:49, 28 July 2024 Nikolas talk contribs created page 13. Tumors of head and neck (Created page with "= Head and neck cancer in general = {{#lst:Head and neck cancer|oncology}} = Oral cavity and oropharynx cancer = {{#lst:Oral cavity and oropharynx cancer|oncology}} = Nasopharynx cancer = {{#lst:Nasopharynx cancer|oncology}} = Hypopharynx cancer = {{#lst:Hypopharynx cancer|oncology}} = Larynx cancer = {{#lst:Laryngeal cancer|oncology}} Category:Oncology (POTE course)") Tag: Visual edit
13:36, 28 July 2024 Nikolas talk contribs created page Head and neck cancer (Created page with "<section begin="oncology" /> * Tumours of the head and neck include ** Eye and orbital tumours ** Oral cavity cancer ** Pharyngeal tumours *** Nasopharynx *** Oropharynx *** Hypopharynx ** Laryngeal tumours *** Supraglottic *** Glottic *** Subglottic ** Tumours of the nasal cavity and paranasal sinuses ** Tumours of the salivary gland ** Tumours of the thyroid gla...") Tag: Visual edit: Switched
09:24, 27 July 2024 Nikolas talk contribs created page 11. Oncologic emergencies (Created page with "{{#lst:Oncologic emergencies|oncology}} Category:Oncology (POTE course)") Tag: Visual edit
09:23, 27 July 2024 Nikolas talk contribs created page Oncologic emergencies (Created page with "<section begin="oncology" /> * In case of oncological emergencies oncotherapy can be initiated without knowing the histology of the cancer * Increased intracranial pressure ** Due to brain metastases or primary brain tumor ** Urgent MRI should be made ** ASAP treatment includes dexamethasone, forced diuresis (fluid + loop diuretics) and mannitol to reduce oedema ** Then treat tumor * Spinal cord compression ** Due to enlarging vertebral metastasis or pathologic vertebral...") Tag: Visual edit: Switched
09:20, 27 July 2024 Nikolas talk contribs created page 12. Palliative care (Created page with "{{#lst:Palliative care|oncology}} Category:Oncology (POTE course)") Tag: Visual edit
09:19, 27 July 2024 Nikolas talk contribs created page 9. Cancer pain management (Created page with "See topic 12. Category:Oncology (POTE course)")
09:19, 27 July 2024 Nikolas talk contribs created page Palliative care (Created page with "<section begin="oncology" />'''Palliative care''' refers to an approach that attempts to improve the quality of life of patients and their close ones and to relieve their suffering. It's most frequently used in life-threatening diseases, most commonly cancer. Palliative care is a symptomatic approach, aiming to relieve symptoms; it does not involve disease-specific treatment. Treatment of pain, distress, anxiety, and nausea/vomiting are the cornerstones. Palliative...") Tag: Visual edit: Switched
08:54, 27 July 2024 Nikolas talk contribs created page Category:Oncology (Created blank page) Tag: Visual edit
08:53, 27 July 2024 Nikolas talk contribs created page Radiotherapy (Redirected page to Radiation oncology#Radiation therapy) Tags: New redirect Visual edit
08:51, 27 July 2024 Nikolas talk contribs created page 8. Biological therapy, targeted therapy and immunotherapy (Created page with "= Targeted therapy = {{#lst:Targeted therapy|oncology}} = Immunotherapy = {{#lst:Immunotherapy|oncology}} Category:Oncology (POTE course)") Tag: Visual edit
08:51, 27 July 2024 Nikolas talk contribs created page Immunotherapy (Created page with "<section begin="oncology" />'''Immunotherapy''' or '''cancer immunotherapy''' refers to using drugs which indirectly stimulate the immune system to treat cancer. * Immune checkpoint inhibitors ** Most commonly used immunotherapy ** These drugs are monoclonal antibodies and therefore also technically biological drugs ** These drugs inhibit the mechanism by which cancer cells inhibit the immune system ** Anti-PD-1 – nivolumab, pembrolizumab ** Anti-CTLA-4 – ipilim...") Tag: Visual edit: Switched
08:48, 27 July 2024 Nikolas talk contribs created page Targeted therapy (Created page with "<section begin="oncology" />'''Targeted therapy''' or '''targeted molecular therapy''' refers to using drugs which are not cytotoxic but rather specifically target certain molecules to treat cancer. Targeted therapy often prolongs survival, sometimes for years, and the patient remains on the targeted therapy during this time. * Biological therapy ** = refers to biological drugs, most commonly monoclonal antibodies ** Bevacizumab – anti-VEGF *** Inhibits vascular p...") Tag: Visual edit: Switched
08:44, 27 July 2024 Nikolas talk contribs created page 6. Basic concepts of chemotherapy (Created page with "{{#lst:Chemotherapy|oncology1}} Category:Oncology (POTE course)") Tag: Visual edit: Switched
08:44, 27 July 2024 Nikolas talk contribs created page Chemotherapy (Created page with "* Polychemotherapy = simultaneous use of multiple chemo drugs ** The term is not consistently used, even by me ** Recently, we have moved to preferring to use multiple chemo drugs, so the term is kind of reduntant * Mode of actions ** Induce DNA damage ** Inhibit DNA repair mechanisms ** Inhibit metabolism *** For example nucleotide synthesis ** Inhibit mitosis ** Inhibit neo-vascularization * Commonly used drugs ** Platinum-based drugs *** Cisplatin **** Very nephrotoxi...") Tag: Visual edit
08:42, 27 July 2024 Nikolas talk contribs created page 5. Treatment planning, radiation protection (Created page with "{{#lst:Radiation oncology|oncology3}} Category:Oncology (POTE course)") Tag: Visual edit
08:42, 27 July 2024 Nikolas talk contribs created page 4. The equipment used in radiation oncology (Created page with "{{#lst:Radiation oncology|oncology2}} Category:Oncology (POTE course)") Tag: Visual edit
08:41, 27 July 2024 Nikolas talk contribs created page 3. Radiation physics (Created page with "{{#lst:Radiation oncology|oncology1}} Category:Oncology (POTE course)") Tag: Visual edit
08:40, 27 July 2024 Nikolas talk contribs created page Radiation oncology (Created page with "== Radiation physics == <section begin="oncology1" /> * Types of radiation used ** Natural radiation (due to radioactive decay) *** Alpha radiation (two protons and two neutrons) *** Beta radiation (high-energy electrons) **** Electrons (beta radiation) has low penetration power, so beta radiation is only suitable for treating tumours near the skin surface ** Gamma radiation (high-energy photons) *** Photon radiation (gamma and X-ray radiation) has high penetration power...") Tag: Visual edit: Switched
08:35, 27 July 2024 Nikolas talk contribs created page 2. Principles of surgical oncology (Created page with "{{#lst:Surgical oncology|oncology}} Category:Oncology (POTE course)") Tag: Visual edit
08:32, 27 July 2024 Nikolas talk contribs created page 1. The basic principles of tumor biology (Created page with "{{#lst:Cancer|oncology}} Category:Oncology (POTE course)") Tag: Visual edit
08:30, 27 July 2024 Nikolas talk contribs created page Cancer (Created page with "{{:Stub}} '''Cancer''' is a group of diseases characterised by abnormal and increased cell growth. Cancers are common and deadly diseases. == Cancer biology == <section end="oncology" /> * Etiological factors contributing to cancer development ** Environmental exposure *** Asbestos -> mesothelioma, RCC *** Formaldehyde -> nose and nasopharyngeal cc ** Radiation *** Those with childhood leukaemia often develop solid tumours 10 – 20 years after the radiotherapy ** Life...") Tag: Visual edit: Switched
08:25, 27 July 2024 Nikolas talk contribs created page Category:Oncology (POTE course) (Created page with "Category:4th year") Tag: Visual edit
08:48, 21 July 2024 Nikolas talk contribs created page B18. Cutaneous T-cell lymphomas (Created page with "{{#lst:Cutaneous T-cell lymphomas|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
08:47, 21 July 2024 Nikolas talk contribs created page Cutaneous T-cell lymphomas (Created page with "<section begin="dermatology" /> * Mycosis fungoides ** <abbr>CD4</abbr>+ T-cell lymphoma ** Progresses slowly ** Stage I – patch stage *** Scaly, pruritic, well-demarcated patches ** Stage II – plaque stage *** Scaly, pruritic, well-demarcated plaques *** Large ** Stage III – tumor stage *** Dome-shaped purple or red nodules ** Treatment *** Topical steroids *** Topical chemo *** Phototherapy *** Biological therapy *** Systemic chemo * Sézary syndrome ** Can devel...") Tag: Visual edit
08:45, 21 July 2024 Nikolas talk contribs created page B17. Secondary skin lesions, basics of dermatohistopathology (Created page with "{{#lst:Terminology in dermatology|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
08:44, 21 July 2024 Nikolas talk contribs created page B16. Primary skin lesions, basics of dermatohistopathology (Created page with "{{#lst:Terminology in dermatology|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
08:42, 21 July 2024 Nikolas talk contribs created page Terminology in dermatology (Created page with "<section begin="dermatology1" />== Primary skin lesions == * Flat lesions ** Macule *** A flat skin lesion < 1 cm in size with discolouration ** Patch *** A flat skin lesion > 1 cm in size with discolouration * Infiltrative lesions ** Papule *** An elevated palpable skin lesion < 0,5 cm in size *** Epidermal ** Plaque *** An elevated palpable skin lesion > 0,5 cm in size *** Intradermal ** Tuber *** An elevated palpable skin lesion whose infiltration involves the entire...") Tag: Visual edit: Switched
08:35, 21 July 2024 Nikolas talk contribs created page B15. Cutaneous manifestation of diabetes mellitus (Created page with "{{#lst:Diabetes mellitus|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
08:32, 21 July 2024 Nikolas talk contribs created page B14. Types of allergic skin reactions (Created page with "* Type I hypersensitivity ** Skin reactions *** Angioedema *** Urticaria ** Diagnosis – prick test ** Treatment *** Antihistamines *** Epinephrine * Type II hypersensitivity ** Not important * Type III hypersensitivity – immune complex-mediated ** Cutaneous vasculitis ** Serum sickness ** Treatment *** Steroids * Type IV hypersensitivity ** Type IVa – Allergic contact dermatitis ** Type IVb – Drug-related eosinophilia and systemic symptoms (DRESS) ** Type IVc –...") Tag: Visual edit
08:28, 21 July 2024 Nikolas talk contribs created page B13. Lyme Borreliosis (Created page with "{{#lst:Lyme disease|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
08:27, 21 July 2024 Nikolas talk contribs created page Lyme disease (Created page with "<section begin="dermatology" />* Tick-borne * Borrelia burgdorferi * Clinical features ** Stage I – early localized Lyme disease *** Within 7 – 14 days *** Erythema migrans **** Circular, slowly-expanding red ring with central clearing around the bite site **** Target-like rash *** Flu-like symptoms ** Stage II – early disseminated Lyme disease *** Multiple erythema migrans *** Migratory arthralgia *** Early neuroborreliosis *** Lyme carditis ** Stage III – late...") Tag: Visual edit
08:24, 21 July 2024 Nikolas talk contribs created page B12. Photodermatoses and phototherapy (Created page with "= Photodermatoses = {{#lst:Photodermatoses|dermatology}} = Phototherapy = {{#lst:Phototherapy|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
08:23, 21 July 2024 Nikolas talk contribs created page Phototherapy (Created page with "<section begin="dermatology" />* Indications ** Psoriasis ** Atopic dermatitis ** Alopecia areata ** Granuloma annulare ** Cutaneous T-cell lymphoma ** Vitilligo ** Photodermatoses ** BCC ** Actinic keratosis * Mechanisms ** Thickens epidermis ** Hyperpigmentation ** Immunosuppressive effect ** Anti-tumor effect * Procedure ** Minimal erythematous dose (MED) is determined ** The dose of UV light depends on the MED * Types ** Narrow-band UVB ** Broad-band UVB ** Selective...") Tag: Visual edit: Switched
08:21, 21 July 2024 Nikolas talk contribs created page Photodermatoses (Created page with "<section begin="dermatology" />* Photodermatoses – skin diseases that develop due to light exposure * Photodermatoses of unknown origin ** Solar dermatitis = sunburn *** UVB radiation causes apoptosis of keratinocytes -> release of inflammatory cytokines *** Clinical features **** Pruritus, pain **** Erythema, oedema **** Blisters (severe) *** Treatment **** Wet compress **** Cooling ointments **** Topical steroids ** Polymorphous light eruption (PLE) *** Chronic disea...") Tag: Visual edit: Switched
08:19, 21 July 2024 Nikolas talk contribs created page B11. Tuberculosis of the skin and its treatment (Created page with "{{#lst:Tuberculosis|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
08:19, 21 July 2024 Nikolas talk contribs created page Tuberculosis (Created page with "{{:Stub}} <section begin="dermatology" />* Cutaneous tb is a rare form of extrapulmonary tb * Multiple types ** Tuberculous chancre *** Occurs at the site where m. tuberculosis enters the skin *** In people who don’t already have TB *** Papule -> painless ulcer ** TB verrucosa cutis *** Occurs at the site where m. tuberculosis enters the skin *** In people who already have TB *** Purplish warty growth ** Lupus vulgaris *** Apple-jelly nodules (gelatinous consistency)...") Tag: Visual edit: Switched
08:15, 21 July 2024 Nikolas talk contribs created page B10. Rosacea, rhinophyma (Created page with "{{#lst:Rosacea|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
08:15, 21 July 2024 Nikolas talk contribs created page Rosacea (Created page with "<section begin="dermatology" />* Chronic inflammatory skin disease * More common in females * Triggers ** Alcohol ** Stress ** Smoking ** Hot weather * Clinical features ** No comedones or seborrhoea ** Erythematotelangiectatic rosacea *** Central facial erythema *** Telangiectasia ** Papulopustular rosacea *** Papules, pustules and erythema ** Phymatous rosacea *** Skin thickens *** Inflammatory nodules *** Rhinophyma – large, bulbous nose ** Ocular rosacea *** Conjun...") Tag: Visual edit: Switched
08:10, 21 July 2024 Nikolas talk contribs created page B9. Paraneoplastic skin disorders (Created page with "{{#lst:Paraneoplastic syndrome|dermatology}} Category:Dermatology (POTE course)") Tag: Visual edit
08:09, 21 July 2024 Nikolas talk contribs deleted page Symptoms and signs of cancer (B symptoms) (content was: " == Constitutional symptoms ("B symptoms") == Cancer may cause many different non-specific symptoms. These are so-called constitutional symptoms. Three constitutional symptoms for malignancy are especially well known. These are the so-called "B symptoms": * Fever (38°C at least) * ''Drenching'' night sweats (the clothes and bed sheets are soaked through by sweat) * Unintent...", and the only contributor was "Nikolas" (talk))
08:00, 21 July 2024 Nikolas talk contribs created page Paraneoplastic syndrome (Created page with "'''Paraneoplastic''' '''syndrome''' refers to any sign or symptom which occurs due to hormone or cytokine production by tumour cells, or by the immune response to the malignancy. Generally, it's defined as any syndrome due to non-metastatic effects of the malignancy. Paraneoplastic syndromes are rare, occuring in somewhere from 2-20% of malignancies. They often develop before the cancer diagnosis. It’s important to recognise these diseases because they can give earlie...") Tag: Visual edit
07:59, 21 July 2024 Nikolas talk contribs created page Paraneoplastic neurological syndromes (Created page with "<section begin="neurology" />Paraneoplastic neurological syndromes occur in 1 – 3% of patients with cancer. They often develop before the cancer diagnosis. They usually occur because the tumour expresses antigens which are structurally similar to antigens on neurons (molecular mimicry). Antineuronal antibodies are often present in the serum and CSF. It’s important to recognise these diseases because they can give earlier diagnosis of the...") Tag: Visual edit
06:41, 21 July 2024 Nikolas talk contribs created page B8. Benign tumours of the skin (Created page with "= Seborrheic keratosis = {{#lst:seborrheic keratosis|dermatology}} = Keratoacanthoma = {{#lst:Keratoacanthoma|dermatology}} = Dermatofibroma = {{#lst:Dermatofibroma|dermatology}} = Lipoma = {{#lst:Lipoma|dermatology}} = Pyogenic granuloma = {{#lst:Pyogenic granuloma|dermatology}} = Others = * Epidermal origin ** Sebaceous nevus ** Apocrine nevus * Benign mesenchymal tumors ** Acrochordon (skin tag) ** Leiomyoma * Vascular tumors ** Angioma ** Haemangioma * Skin adnexal...") Tag: Visual edit
06:38, 21 July 2024 Nikolas talk contribs created page Pyogenic granuloma (Created page with "<section begin="dermatology" />* Benign vascular tumor * Soft, round, bright red tumor * Bleeds easily due to being vascular * Not actually "pyogenic" * Recurs after removal<section end="dermatology" /> Category:Dermatology") Tag: Visual edit: Switched
06:36, 21 July 2024 Nikolas talk contribs created page Lipoma (Created page with "<section begin="dermatology" />* Slow growing * Round * Soft * “Rubbery”<section end="dermatology" /> Category:Dermatology") Tag: Visual edit: Switched
06:36, 21 July 2024 Nikolas talk contribs created page Dermatofibroma (Created page with "<section begin="dermatology" />* Fibroblasts * Slowly growing * Skin-coloured or brownish nodules * Most commonly on lower extremities * Fitzpatrick sign – when squeezed the surface retracts inwards ** Characteristic for dermatofibroma * Treatment only for cosmetic reasons<section end="dermatology" /> Category:Dermatology") Tag: Visual edit: Switched