Photodermatoses

From greek.doctor
  • Photodermatoses – skin diseases that develop due to light exposure
  • Photodermatoses of unknown origin
    • Solar dermatitis = sunburn
      • UVB radiation causes apoptosis of keratinocytes -> release of inflammatory cytokines
      • Clinical features
        • Pruritus, pain
        • Erythema, oedema
        • Blisters (severe)
      • Treatment
        • Wet compress
        • Cooling ointments
        • Topical steroids
    • Polymorphous light eruption (PLE)
      • Chronic disease
      • In adult females
      • Most common photodermatitis
      • Clinical features
        • Itching, burning erythema
        • Malaise, headache
    • Solar urticaria
      • Rare
      • Type I hypersensitivity
      • Urtica at site of sun exposure
    • Actinic prurigo
    • Chronic actinic dermatitis
  • Photodermatoses of known origin
    • Phototoxic reactions
    • Photoallergic reactions
  • Diagnosis
    • Photo-patch test
      • UVA applied, then patch
      • Read immediately, then at 24, 48, 72 hours
    • Photo-provocation test
      • Differentiate between solar urticaria, chronic actinic dermatitis, polymorphous light eruption, SLE
  • Treatment
    • Photohardening
    • Photoprotection