All public logs
Combined display of all available logs of greek.doctor. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 17:02, 3 April 2024 Nikolas talk contribs created page 19. Laboratory diagnostic approaches in anaemias. (Created page with "= Anaemia = {{#lst:Anaemia|clinical biochemistry}} = Haemolytic anaemia = {{#lst:Haemolytic anaemia|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 16:57, 3 April 2024 Nikolas talk contribs created page 18. Laboratory diagnosis of malignant hematologic disorders; complete blood count and flow cytometry (Created page with "For complete blood count, see topic 17. For diagnosis of multiple myeloma, see topic 15. = Flow cytometry = {{#lst:Flow cytometry|clinical biochemistry}} = Bone marrow aspiration and biopsy = {{#lst:Bone marrow aspirate and biopsy|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 16:53, 3 April 2024 Nikolas talk contribs created page Bone marrow aspirate and biopsy (Created page with "<section begin="clinical biochemistry" />'''Bone marrow aspirate''' and '''bone marrow biopsy''' are two examinations used in the evaluation of the bone marrow, indicated in case of unexplained haemotological disorder (like unexplained anaemia, leukopaenia, etc.) and in the evaluation of leukaemia and lymphoma. Bone marrow aspiration involves aspirating a small part of the liquid bone marrow. This is technically more simple to perform and gives informati...") Tag: Visual edit: Switched
- 21:53, 27 March 2024 Nikolas talk contribs created page Blood smear (Created page with "<section begin="clinical biochemistry" />'''Blood smear''', sometimes called '''peripheral blood smear''' (probably to distinguish it from a bone marrow aspirate?) is a Giemsa stained thin film of blood on a glass microscopic slide. It allows morphological examination of blood cells and platelets. It's used in the evaluation of anaemia and leukaemia. In many types of anaemia there is abnormal morphology of the red blood cells, like in sickle cell anaemia, here...") Tag: Visual edit: Switched
- 21:25, 27 March 2024 Nikolas talk contribs created page 17. Laboratory findings in inflammatory disorders (Created page with "= Leukocytes = {{#lst:Leukocyte|clinical biochemistry}} = C-reactive protein = {{#lst:C-reactive protein|clinical biochemistry}} = Procalcitonin = {{#lst:Procalcitonin|clinical biochemistry}} = Erythrocyte sedimentation rate = {{#lst:Erythrocyte sedimentation rate|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 09:44, 27 March 2024 Nikolas talk contribs created page Erythrocyte sedimentation rate (Created page with "<section begin="clinical biochemistry" />'''Erythrocyte sedimentation rate''' (ESR), also called the '''Westergren method''' (We), is a laboratory measurement of how quickly the erythrocytes in a sample sediment (settle on the bottom of the tube). The ESR increases in response to the acute phase reaction (inflammation), but it takes many days for the ESR to increase following an inflammation, and it takes weeks to normalise. The normal value depends on age and ge...") Tag: Visual edit: Switched
- 09:27, 27 March 2024 Nikolas talk contribs moved page Leukocytes to Leukocyte
- 09:22, 27 March 2024 Nikolas talk contribs created page Acute phase reaction (Redirected page to Acute phase proteins) Tags: New redirect Visual edit
- 09:21, 27 March 2024 Nikolas talk contribs created page B48. The notion and statement of brain death. Medico-legal prerequisites. (Created page with "{{:Brain death}} Category:Surgery final (POTE course)") Tag: Visual edit
- 20:41, 26 March 2024 Nikolas talk contribs created page Procalcitonin (Created page with "<section begin="clinical biochemistry" />'''Procalcitonin''' (PCT) is a prohormone for calcitonin, a calcium-regulating hormone. The level of PCT increases in case of some infections. PCT used to look very promising as a tool to distinguish between bacterial infection and other causes of inflammation (as a more specific alternative to CRP), but more recent research have dampened these hopes as it turns out to not be as specific for bacterial infections as previou...") Tag: Visual edit: Switched
- 20:17, 26 March 2024 Nikolas talk contribs created page 16. Assessment of acute phase proteins, diagnosis and monitoring of sepsis (Created page with "= Acute phase proteins = {{#lst:Acute phase proteins|clinical biochemistry}} = Sepsis = {{#lst:Sepsis|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 20:15, 26 March 2024 Nikolas talk contribs created page Sepsis (Created page with "<section begin="pathophysiology" /><section begin="clinical biochemistry" />'''Sepsis''' is an acute life-threatening condition characterised by organ dysfunction caused by a dysregulated host response to infection, usually bacterial. It’s related to SIRS in pathomechanism. It has a very high mortality rate and can lead to multiple organ dysfunction syndrome (MODS) and death.<section end="clinical biochemistry" /> == Definition == Sepsis is accurately defined as “A...") Tag: Visual edit
- 20:04, 26 March 2024 Nikolas talk contribs created page Acute phase proteins (Created page with "<section begin="clinical biochemistry" />'''Acute phase proteins''' (APPs), also called '''acute phase reactants''', are proteins whose synthesis is up- or downregulated in case of inflammation, both acute and chronic (despite the name). This is called the '''acute phase reaction''' or '''acute phase response''', which is part of the body's defence against microbes. Acute phase proteins are produced in the liver. == Triggers of the acute phase reaction == When certa...") Tag: Visual edit: Switched
- 19:32, 26 March 2024 Nikolas talk contribs created page 15. Disorders of immunoglobulins and paraproteins (Created page with "= Monoclonal gammopathy = {{#lst:Monoclonal gammopathy|clinical biochemistry}} = Multiple myeloma = {{#lst:Multiple myeloma|clinical biochemistry}} = Polyclonal gammopathy = {{#lst:Polyclonal gammopathy|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 19:31, 26 March 2024 Nikolas talk contribs created page Polyclonal gammopathy (Created page with "<section begin="clinical biochemistry" />'''Polyclonal gammopathy''' refers to any condition where there is excessive amounts of polyclonal gammaglobulin in the blood. Polyclonal gammopathy is the opposite of monoclonal gammopathy. Polyclonal gammopathy is a part of the regular immunologial response to any infection and many forms of inflammation, where B cells produce antibodies (immunoglobulins).<section end="clinical biochemistry" /> Category:Pathology") Tag: Visual edit: Switched
- 19:25, 26 March 2024 Nikolas talk contribs created page Monoclonal gammopathy (Created page with "<section begin="clinical biochemistry" />'''Monoclonal gammopathy''' refers to any condition where there is excessive amounts of a monoclonal gammaglobulin in the blood. These monoclonal gammaglobulins are called "M proteins". Monoclonal gammopathy is the opposite of polyclonal gammopathy. The following are the most common monoclonal gammopathies: * Monoclonal gammopathy of unknown significance (most common) * Multiple myeloma * Waldenström macro...") Tag: Visual edit: Switched
- 19:18, 26 March 2024 Nikolas talk contribs created page 14. Disturbances of non-immunoglobulin plasma proteins (Created page with "= Albumin = {{#lst:Albumin|clinical biochemistry}} = Prealbumin = {{#lst:Prealbumin|clinical biochemistry}} = Alpha-1 antitrypsin = {{#lst:Alpha-1 antitrypsin|clinical biochemistry}} = Alpha-1 microglobulin = {{#lst:Alpha-1 microglobulin|clinical biochemistry}} = Beta-2 microglobulin = {{#lst:Beta-2 microglobulin|clinical biochemistry}} = Caeruloplasmin = {{#lst:Caeruloplasmin|clinical biochemistry}} = Thyroid-binding globulin = {{#lst:Thyroid-binding globulin|clinical b...") Tag: Visual edit
- 15:23, 26 March 2024 Nikolas talk contribs created page Thyroid-binding globulin (Created page with "'''Thyroid-binding globulin''' is a globular plasma protein whose function is to bind and transport thyroxine and triiodothyronine.") Tag: Visual edit
- 15:14, 26 March 2024 Nikolas talk contribs created page Sex hormone binding globulin (Created page with "<section begin="clinical biochemistry" />'''Sex hormone binding globulin''' (SHBG) is a globular plasma protein whose function is to bind and transport testosterone, dihydrotestosterone, and oestradiol. Measurement of SHBG is important because only the unbound fraction of sex hormones in the plasma is biologically active, and so when evaluating sex hormonal disorders one can only determine the biologically active fraction of sex hormones is one also knows th...") Tag: Visual edit: Switched
- 15:06, 26 March 2024 Nikolas talk contribs created page Caeruloplasmin (Created page with "<section begin="clinical biochemistry" />'''Caeruloplasmin''' is a copper-binding plasma protein synthesised in the liver. It's a positive acute phase protein. Low levels of caeruloplasmin is suggestive (but not diagnostic of) Wilson disease.<section end="clinical biochemistry" /> Category:Physiology") Tag: Visual edit: Switched
- 15:03, 26 March 2024 Nikolas talk contribs created page Beta-2 microglobulin (Created page with "<section begin="clinical biochemistry" />'''Beta-2 microglobulin''' is a globular plasma protein and a component of MHC class I molecules, meaning that it exists on all nucleated cells. It can be measured in the urine as a marker of proteinuria. Elevated levels is a poor prognostic factor in lymphoma, chronic lymphocytic leukaemia, multiple myeloma, and AIDS.<section end="clinical biochemistry" /> Category:Physiology") Tag: Visual edit: Switched
- 15:02, 26 March 2024 Nikolas talk contribs created page Chronic lymphocytic leukaemia (Redirected page to Chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL)) Tags: New redirect Visual edit
- 14:55, 26 March 2024 Nikolas talk contribs created page Alpha-1 microglobulin (Created page with "<section begin="clinical biochemistry" />'''Alpha-1 microglobulin''' (A1M) is a small globular plasma protein synthesised by the liver. Its function is to bind and degrade haeme. It's not a very important molecule clinically. It may be measured in urine as an indicator of proteinuria.<section end="clinical biochemistry" /> Category:Physiology") Tag: Visual edit: Switched
- 14:52, 26 March 2024 Nikolas talk contribs created page Alpha-1 antitrypsin (Created page with "{{:Stub}} <section begin="clinical biochemistry" />'''Alpha-1 antitrypsin''' (A1AT) is a plasma protein and a protease inhibitor. It protects tissues from proteases like neutrophil elastase. Alpha-1 antitrypsin deficiency predisposes to pulmonary emphysema (a form of COPD) and cirrhosis.<section end="clinical biochemistry" /> Category:Physiology") Tag: Visual edit: Switched
- 14:47, 26 March 2024 Nikolas talk contribs created page Albumin (Created page with "<section begin="clinical biochemistry" />'''Albumin''', more specifically '''human serum albumin''', is a plasma protein whose main function is to transport bioactive molecules and to maintain oncotic pressure. It's a negative acute phase protein. Bisalbuminaemia is a harmless disorder where a person has two "peaks" in the albumin fraction on serum electrophoresis, showing that the person produces both normal and a mutated abnormal albumin.<section end="...") Tag: Visual edit: Switched
- 14:42, 26 March 2024 Nikolas talk contribs moved page Plasma proteins to Plasma protein
- 14:38, 26 March 2024 Nikolas talk contribs created page Prealbumin (Created page with "{{:Stub}} '''Prealbumin''' is a negative acute phase protein. It binds thyroxin (T3) and vitamin A in the serum. It's sometimes used as a marker of nutritional status but it performs very poorly as such a marker. Category:Physiology") Tag: Visual edit
- 14:35, 26 March 2024 Nikolas talk contribs created page 13. Laboratory analysis of plasma enzymes (Created page with "* Enzymes ** Measurement based on enzyme activity ** Enzyme + substrate -> *** coloured product -> photometry *** or a secondary reaction which forms a coloured product -> photometry *** or there is a change in NADH -> photometry with UV light ** 1 unit = 1 µmol substrate per minute ** U/L = µmol/min/L * Most frequently measured enzymes ** ASAT ** ALAT ** GGT ** ALP ** LDH ** CK ** Amylase ** Lipase Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 21:45, 21 March 2024 Nikolas talk contribs created page 12. Laboratory analysis of plasma proteins (Created page with "= Plasma proteins = {{#lst:plasma proteins|clinical biochemistry}} = Serum electrophoresis = {{#lst:serum electrophoresis|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 21:42, 21 March 2024 Nikolas talk contribs created page Serum electrophoresis (Created page with "{{:Stub}} <section begin="clinical biochemistry" /> * Serum electrophoresis ** Prealbumin=transthyretin ** Albumin ** Alpha-1 band *** alpha1-antitrypsin *** alpha1-acid glycoprotein (AGP) *** alpha1-microglobulin ** Alpha-2 band *** Haptoglobin *** alpha2-macroglobulin *** Caeruloplasmin ** Beta band *** Transferrin *** Beta2-microglobulin *** Complement factors ** Between beta and gamma *** CRP ** Gamma band *** Immunoglobulins <section end="clinical biochemistry" /> [...") Tag: Visual edit: Switched
- 21:40, 21 March 2024 Nikolas talk contribs created page Plasma proteins (Created page with "{{:Stub}} <section begin="clinical biochemistry" /> * Total protein ** Biuret test (copper forms purple complex with proteins in alkaline solution) ** Colour intensity proportional to protein concentration – photometry * Albumin ** Albumin forms green complex with BCG at pH 4,1 ** Photometry * Specific proteins ** Measurement based on immunogenicity – use of monoclonal or polyclonal antibodies ** Immunoassay – biochemical test measuring concentration of protein b...") Tag: Visual edit: Switched
- 21:38, 21 March 2024 Nikolas talk contribs created page 11. Clinical biochemistry of osteoporosis. Laboratory tests to assess joint and bone disorders. (Created page with "= Bone = {{#lst:bone|clinical biochemistry}} = Osteoporosis = {{#lst:osteoporosis|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 21:30, 21 March 2024 Nikolas talk contribs created page Bone (Created page with "{{:stub}} <section begin="clinical biochemistry" /> * bone ** 65% minerals (hydroxyapatite) ** 35% matrix *** Collagen *** Osteoblasts *** Osteoclasts * Markers ** High biological and analytical variability *** Diurnal variation *** Seasonal variation *** Food intake *** Exercise ** Made in same lab, collected at same time * Markers of bone formation ** Total alkaline phosphatase ** '''Bone specific alkaline phosphatase''' ** Osteocalcin – increased in high bone turno...") Tag: Visual edit: Switched
- 21:26, 21 March 2024 Nikolas talk contribs created page 10. Laboratory approaches for the detection of disorders in calcium, magnesium and phosphate homeostasis (Created page with "= Calcium = {{#lst:calcium|clinical biochemistry}} = Hypocalcaemia = {{#lst:hypocalcaemia|clinical biochemistry}} = Hypercalcaemia = {{#lst:hypercalcaemia|clinical biochemistry}} = Magnesium = {{#lst:magnesium|clinical biochemistry}} = Hypomagnesaemia = {{#lst:hypomagnesaemia|clinical biochemistry}} = Hypermagnesaemia = {{#lst:hypermagnesaemia|clinical biochemistry}} = Phosphate = {{#lst:phosphate|clinical biochemistry}} = Hypophosphataemia = {{#lst:hypophosphataemia|cli...") Tag: Visual edit
- 21:23, 21 March 2024 Nikolas talk contribs created page Calcium (Created page with "{{:Stub}}<section begin="clinical biochemistry" /> '''Calcium''' is an ion in the body. * Roles ** Comprises bone ** 1 kg in adults *** 99% in bone ** Muscle contraction ** Neurotransmission ** Membrane transport ** Enzymes ** Coagulation * 45% free * 45% protein bound * 10% anion bound * Regulation ** Kidney ** PTH *** Decreased calcium stimulates PTH *** Increased phosphate stimulates PTH *** Increases Ca2+ reabsorption in tubule *** Increases phosphate excretion in...") Tag: Visual edit
- 21:20, 21 March 2024 Nikolas talk contribs created page Hyperphosphataema (Created page with "{{:Stub}} <section begin="clinical biochemistry" />'''Hyperphosphataemia''' refers to a pathologically high phosphate level, approximately > 1,50 mmol/L. It can be present in case of chronic kidney disease (most common), tumor lysis syndrome, rhabdomyolysis, acidosis.<section end="clinical biochemistry" /> Category:Pathophysiology") Tag: Visual edit
- 21:18, 21 March 2024 Nikolas talk contribs created page Hypophosphataemia (Created page with "{{:Stub}} <section begin="clinical biochemistry" /> '''Hypophosphataemia''' refers to a pathologically low phosphate level, approximately < 0,75 mmol/L. It can be present in case of alcoholism, malnourishment, hyperparathyroidism.<section end="clinical biochemistry" /> Category:Pathophysiology") Tag: Visual edit: Switched
- 21:14, 21 March 2024 Nikolas talk contribs created page Phosphate (Created page with "{{:Stub}} <section begin="clinical biochemistry" /> '''Phosphate''' is a group of anions in the body. The normal level is approximately 0,75 - 1,50 mmol/L. Most of phosphate in the body exists in the skeleton as part of hydroxyapatite. Pathologically low or high phosphate levels is called hypophosphataemia and hyperphosphataema, respectively. Category:Physiology <section end="clinical biochemistry" />") Tag: Visual edit: Switched
- 21:09, 21 March 2024 Nikolas talk contribs created page Hyperchloraemia (Created page with "{{:Stub}} <section begin="clinical biochemistry" /> * Hyperchloraemia ** (Normal anion gap) Metabolic acidosis (RTA, diarrhoea) ** Dehydration ** Excessive IV saline <section end="clinical biochemistry" /> Category:Pathophysiology") Tag: Visual edit: Switched
- 21:08, 21 March 2024 Nikolas talk contribs created page Hypochloraemia (Created page with "{{:Stub}} <section begin="clinical biochemistry" /> * Hypochloraemia ** Vomiting ** Diuretics ** Metabolic alkalosis <section end="clinical biochemistry" /> Category:Pathophysiology") Tag: Visual edit: Switched
- 21:08, 21 March 2024 Nikolas talk contribs created page Chloride (Created page with "{{:Stub}} <section begin="clinical biochemistry" /> * Roles ** Maintains osmolality, electric neutrality, blood volume <section end="clinical biochemistry" /> Category:Physiology") Tag: Visual edit
- 21:06, 21 March 2024 Nikolas talk contribs created page Hypermagnesaemia (Created page with "{{:stub}} <section begin="clinical biochemistry" /> * Hypermagnesaemia ** Renal failure ** Rhabdomyolysis <section end="clinical biochemistry" /> Category:Pathophysiology") Tag: Visual edit
- 21:05, 21 March 2024 Nikolas talk contribs created page Hypomagnesaemia (Created page with "{{:Stub}} <section begin="clinical biochemistry" /> * Hypomagnesaemia ** Malnutrition ** Laxative abuse ** Hyperparathyroidism <section end="clinical biochemistry" /> Category:Pathophysiology") Tag: Visual edit
- 21:04, 21 March 2024 Nikolas talk contribs created page Magnesium (Created page with "{{:Stub}} <section begin="clinical biochemistry" /> * Roles ** Enzyme cofactor ** Calcium homeostasis *** Magnesium is a calcium antagonist, prevents intracellular accumulation of calcium <section end="clinical biochemistry" /> Category:Physiology") Tag: Visual edit: Switched
- 16:37, 4 March 2024 Nikolas talk contribs created page Hypercalcaemia (Created page with "'''Hypercalcaemia''' is a disorder of calcium homeostasis characterised by high levels of calcium (free calcium > 1,30 mmol/L). It's a relatively common electrolyte abnormality and is the opposite of hypocalcaemia. A free calcium level of > 2,00 is sometimes called a '''hypercalcaemic crisis'''. 99% of the body's calcium is in the bones. The remaining 1% is in the blood. 40% of calcium in the serum is bound to albumin, 10% is bound to other anions (lactate and...") Tag: Visual edit
- 20:19, 1 March 2024 Nikolas talk contribs created page Hypocalcaemia (Created page with "'''Hypocalcaemia''' is a disorder of calcium homeostasis characterised by low levels of calcium. It's a relatively common electrolyte abnormality. == Grading of severity == {| class="wikitable" |+ !Total calcium level !Free calcium level !Albumin-corrected calcium level !Severity |- | |1,14 - 1,00 |2,14 - 1,90 |Mild |- | |0,99 - 0,80 |1,89 - 1,65 |Moderate |- | |< 0,80 |< 1,65 |Severe |}") Tag: Visual edit
- 20:06, 1 March 2024 Nikolas talk contribs created page 9. Laboratory findings in respiratory type changes of the acid/base balance (Created page with "= Respiratory acidosis = {{#lst:Respiratory acidosis|clinical biochemistry}} = Respiratory alkalosis = {{#lst:Respiratory alkalosis|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 22:00, 29 February 2024 Nikolas talk contribs created page 8. Laboratory findings in metabolic type changes of the acid/base balance (Created page with "= Metabolic acidosis = {{#lst:Metabolic acidosis|clinical biochemistry}} = Metabolic alkalosis = {{#lst:Metabolic alkalosis|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 21:55, 29 February 2024 Nikolas talk contribs created page Respiratory alkalosis (Created page with "'''Respiratory alkalosis''' is an acid-base disorder characterised by a respiratory pathological process which increases the pH of the blood. If the alkalosis is severe, it can overcome the body's defense against alkalosis, causes the pH in the blood to increase beyond 7.45. This is called alkalaemia. Metabolic alkalosis is similar but is rather due to a metabolic problem. Respiratory acidosis is sort of the opposite of respiratory alkalosis. Respiratory al...") Tag: Visual edit: Switched
- 21:07, 28 February 2024 Nikolas talk contribs created page Emphysema (Redirected page to Chronic obstructive pulmonary disease) Tags: New redirect Visual edit