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10. Rapidly progressive GN with crescents: Difference between revisions
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## <abbr>IgA</abbr> nephropathy | ## <abbr>IgA</abbr> nephropathy | ||
# Pauci-immune | # Pauci-immune | ||
[[File:RPGN - glomerulus.png|thumb|(Mostly) normal glomerulus. The glomerular tuft occupies mostly the whole Bowman’s space.]]'''Theory''': | [[File:RPGN - glomerulus.png|thumb|(Mostly) normal glomerulus. The glomerular tuft occupies mostly the whole Bowman’s space.|261x261px]]'''Theory''': | ||
Crescents are formed by proliferation of parietal cells and by migration of macrophages into the Bowman’s space. They are comprised of macrophages, fibroblasts, fibrosis and possibly necrosis. | Crescents are formed by proliferation of parietal cells and by migration of macrophages into the Bowman’s space. They are comprised of macrophages, fibroblasts, fibrosis and possibly necrosis. | ||
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Rapidly progressing glomerulonephritis causes rapid renal failure within days. Diagnosis is based on histology. | Rapidly progressing glomerulonephritis causes rapid renal failure within days. Diagnosis is based on histology. | ||
[[File:RPGN - glomerulus2.png|thumb|Another glomerulus|left]] | [[File:RPGN - glomerulus2.png|thumb|Another glomerulus|left]] | ||
[[File:RPGN - glomerulus3.png|thumb|A third glomerulus]] | [[File:RPGN - glomerulus3.png|thumb|A third glomerulus|264x264px]] | ||
[[Category:Pathology 2 - Histopathology slides]] | [[Category:Pathology 2 - Histopathology slides]] | ||