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22. Fibrinous pericarditis – cor villosum: Difference between revisions
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'''Organ''': Heart | '''Organ''': Heart | ||
'''Description''': | '''Description''': The slide is from a cross-section of the heart. Five layers can be distinguished. From the bottom layer to the top layer: | ||
The slide is from a cross-section of the heart. Five layers can be distinguished. From the bottom layer to the top layer: | |||
# The bottom layer is the myocardium. It’s normal. | # The bottom layer is the myocardium. It’s normal. | ||
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'''Diagnosis''': Fibrinous pericarditis = cor villosum | '''Diagnosis''': Fibrinous pericarditis = cor villosum | ||
'''Theory''': | '''Theory''': The fibrinous exudate caused by the fibrinous acute inflammation is mostly degraded by fibrinolysis and macrophages, a process called resolution. However, the fibrin-rich exudate is not completely removed and is instead replace by fibroblasts and blood vessels invading the exudate to form fibrosis. This is the process called organization. | ||
The fibrinous exudate caused by the fibrinous acute inflammation is mostly degraded by fibrinolysis and macrophages, a process called resolution. However, the fibrin-rich exudate is not completely removed and is instead replace by fibroblasts and blood vessels invading the exudate to form fibrosis. This is the process called organization. | |||
The fifth layer (layer 5) shows the ''active'' phase of the pericarditis. It’s comprised of only neutrophils (due to the inflammation) and fibrin. Fibrin, being a protein, is very eosinophilic under the microscope. | The fifth layer (layer 5) shows the ''active'' phase of the pericarditis. It’s comprised of only neutrophils (due to the inflammation) and fibrin. Fibrin, being a protein, is very eosinophilic under the microscope. | ||