Non-HCC liver malignancies

HCC is the most common liver malignancy, but other types exist too.

Intrahepatic cholangiocarcinoma

Intrahepatic cholangiocarcinoma is a rare and aggressive liver cancer. It may also develop on the basis of cirrhosis. It spreads along the bile ducts. Treatment is surgical.

Angiosarcoma

Hepatic angiosarcoma is very rare and aggressive. It’s notably associated with exposure to certain toxins, vinyl chloride and thorium dioxide. Vinyl chloride was formerly used in the plastic industry. Thorium dioxide was a radiocontrast material formerly used.

Hepatoblastoma

Hepatoblastoma is a rare childhood tumor that originates in liver precursor tissue, but it’s the most common primary liver tumour in children (0 – 3 years). It usually presents as an abdominal mass.

Secondary liver malignancy

Liver metastases usually spread from colorectal carcinoma.

Liver metastasectomy may be used for multiple types of secondary liver cancers, most commonly CRC. Patients with primary colorectal cancer with liver metastasis may undergo metastasectomy with curative intent.

Metastasectomy or debulking may also be used in neuroendocrine, breast, gynaecological, or other secondary liver cancers.