49. Radionuclide therapy of neuroendocrine and neuroectodermal tumors.

From greek.doctor
  • Neuroendocrine (carcinoid) tumors express somatostatin receptors -> radiopharmaceuticals will bind to these receptors
    • Indications
      • Lung neuroendocrine tumors
      • Adenocarcinomas of GI tract and pancreas
    • Radiopharmaceuticals which bind to SST receptors
      • 111In-octreotide – indium-111-octreotide
      • 99mTc-depreotide
  • I123-MIBG scintigraphy
    • I123-MIBG binds to adrenergic receptors in neuroendocrine tumors
    • Indications
      • Neuroblastoma
      • Phaeochromocytoma
    • Thyroid must be protected from radiation
      • Iodine is given before examination