35. Mixed germ cell tumor with teratoma and embryonal carcinoma

From greek.doctor
Overview. Most of the slide is teratoma.

Staining: HE

Organ: Testis

Description:

Two tumors are present on the slide.

The teratoma takes up most of the slide. It shows widespread necrosis. Tissues from multiple germ layers are visible, which confirms that it’s a teratoma.

The embryonal carcinoma is in the lower right corner. These tumor cells show severe atypia. Necrosis is visible here as well.

Diagnosis: Mixed germ cell tumor with teratoma and embryonal carcinoma

Risk factors:

  • 20 – 30 year old males

Theory:

Nothing in particular.

From the circulated area. Cartilage and smooth muscle arise from the mesoderm, while ductal epithelium arise from the endoderm, showing that this is a teratoma.
From the embryonal carcinoma. The tumor cells show severe atypia.