30. Lymphomatous polyposis of small and large intestine
Organ: Large intestine
Description:
The mucus membrane of the intestine is filled with polyps.
Diagnosis: Lymphomatous polyposis (due to mantle cell lymphoma)
Causes:
- Translocation of cyclin D1 gene into IgH gene – t(11;14)
Theory:
Like the case was for the Burkitt lymphoma – there’s no way to diagnose these polyps as mantle cell lymphoma without histology. These polyps could also be due to:
- Familiar adenomatous polyposis
- Ulcerative colitis
- Hamartomatous polyps