Bone
This article is a stub, meaning that it is unfinished. It will eventually be expanded.
- bone
- 65% minerals (hydroxyapatite)
- 35% matrix
- Collagen
- Osteoblasts
- Osteoclasts
- Markers
- High biological and analytical variability
- Diurnal variation
- Seasonal variation
- Food intake
- Exercise
- Made in same lab, collected at same time
- High biological and analytical variability
- Markers of bone formation
- Total alkaline phosphatase
- Bone specific alkaline phosphatase
- Osteocalcin – increased in high bone turnover
- Procollagen propeptides
- PICP – procollagen type I C-terminal
- PINP – procollagen type I N-terminal
- Markers of bone resorption
- Urine (corrected for creatinine)
- Deoxypyridinoline (cross-linking collagen cleavage products)
- N-terminal cross links (NTX) – N-telopeptide of type I collagen
- C-terminal cross links (CTX) – C-telopeptide of type I collagen
- Serum
- TRACP5b – tartate resistant acid phosphatase
- Serum and urine
- beta-crosslaps
- Urine (corrected for creatinine)