Calcium

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Revision as of 22:23, 21 March 2024 by Nikolas (talk | contribs) (Created page with "{{:Stub}}<section begin="clinical biochemistry" /> '''Calcium''' is an ion in the body. * Roles ** Comprises bone ** 1 kg in adults *** 99% in bone ** Muscle contraction ** Neurotransmission ** Membrane transport ** Enzymes ** Coagulation * 45% free * 45% protein bound * 10% anion bound * Regulation ** Kidney ** PTH *** Decreased calcium stimulates PTH *** Increased phosphate stimulates PTH *** Increases Ca2+ reabsorption in tubule *** Increases phosphate excretion in...")
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Calcium is an ion in the body.

  • Roles
    • Comprises bone
    • 1 kg in adults
      • 99% in bone
    • Muscle contraction
    • Neurotransmission
    • Membrane transport
    • Enzymes
    • Coagulation
  • 45% free
  • 45% protein bound
  • 10% anion bound
  • Regulation
    • Kidney
    • PTH
      • Decreased calcium stimulates PTH
      • Increased phosphate stimulates PTH
      • Increases Ca2+ reabsorption in tubule
      • Increases phosphate excretion in tubule
      • Increases vitamin D production
      • Increases bone resorption
    • Vitamin D
      • Increases Ca2+ reabsorption in tubule
      • Increases Ca2+ reabsorption in GI tract
      • Decrease phosphate excretion in tubule
      • Increase bone mineralization
    • (Calcitonin)
      • Opposite of PTH
      • Tumor marker