26. Epidemiology and prevention of inflammatory bowel diseases
- IBD
- Epidemiology
- More common in urbanized areas of Western countries
- Higher incidence in northern than southern countries
- White, Ashkenazi Jews
- Age of onset 15 – 30
- Women = men
- Etiology
- Physical inactivity
- Diet
- Low intake of fibre
- High intake of fat
- Vitamin D deficiency
- Hygiene hypothesis
- Extremely hygienic environments predispose to immunological diseases
- Family history
- High socioeconomic status
- Urbanization
- Drugs
- Contraceptives
- NSAIDs
- Prognosis
- No cure
- Mortality similar to healthy
- Needs a lifetime of care
- Requires many physician visits, hospitalizations
- Major cause of disability
- Prevention
- Tertiary
- Epidemiology
- Crohns
- Epidemiology
- Prevalence: 300 / 100 000
- Incidence: 24 / 100 000
- Specific risk factors
- Smoking
- NOD2
- Prognosis
- 75% require surgery
- Epidemiology
- UC
- Epidemiology
- Prevalence: 500 / 100 000
- Incidence: 12 / 100 000
- Specific risk factors
- Not smoking
- Prognosis
- 25% require surgery
- Epidemiology