26. Epidemiology and prevention of inflammatory bowel diseases

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Revision as of 20:44, 30 November 2022 by Nikolas (talk | contribs) (Created page with "* IBD ** Epidemiology *** More common in urbanized areas of Western countries *** Higher incidence in northern than southern countries *** White, Ashkenazi Jews *** Age of onset 15 – 30 *** Women = men ** Etiology *** Physical inactivity *** Diet **** Low intake of fibre **** High intake of fat **** Vitamin D deficiency *** Hygiene hypothesis **** Extremely hygienic environments predispose to immunological diseases *** Family history *** High socioeconomic status *** U...")
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  • IBD
    • Epidemiology
      • More common in urbanized areas of Western countries
      • Higher incidence in northern than southern countries
      • White, Ashkenazi Jews
      • Age of onset 15 – 30
      • Women = men
    • Etiology
      • Physical inactivity
      • Diet
        • Low intake of fibre
        • High intake of fat
        • Vitamin D deficiency
      • Hygiene hypothesis
        • Extremely hygienic environments predispose to immunological diseases
      • Family history
      • High socioeconomic status
      • Urbanization
      • Drugs
        • Contraceptives
        • NSAIDs
    • Prognosis
      • No cure
      • Mortality similar to healthy
      • Needs a lifetime of care
      • Requires many physician visits, hospitalizations
      • Major cause of disability
    • Prevention
      • Tertiary
  • Crohns
    • Epidemiology
      • Prevalence: 300 / 100 000
      • Incidence: 24 / 100 000
    • Specific risk factors
      • Smoking
      • NOD2
    • Prognosis
      • 75% require surgery
  • UC
    • Epidemiology
      • Prevalence: 500 / 100 000
      • Incidence: 12 / 100 000
    • Specific risk factors
      • Not smoking
    • Prognosis
      • 25% require surgery