20. Epidemiology and prevention of osteoporosis
- Epidemiology
- 4x in women
- Women mostly primary osteoporosis
- Men mostly secondary osteoporosis
- Age of onset 50 – 70
- Asian, Hispanic, European > black
- 4x in women
- Etiology
- Female
- White
- Old age
- Malnutrition
- Poor protein, calcium, vitamin D intake
- Family history
- Smoking
- Alcohol
- Diagnosis:
- DEXA scan, which measures the bone mineral density (BMD)
- T-score: the number of standard deviations the patient’s BMD is away from the BMD of a young female adult
- Osteopaenia: T-score -2,5 <-> -1
- Osteoporosis: T-score < -2.5
- Z-score: the number of standard deviations the patient is away from a similarly aged adult
- Prognosis
- 30 – 50% of women will experience fracture related to osteoporosis during lifetime
- Prevention
- Avoid alcohol
- Avoid smoking
- Sufficient intake of Ca
- Sufficient intake of vitamin D
- Physical activity – strength training
- Bisphosphonates