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22. Glioblastoma: Difference between revisions
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Glioblastoma is a grade IV astrocytic tumor that is defined histologically be the four characteristics described above. It must be differentiated from ''anaplastic astrocytoma'', a grade III astrocytic tumor. Anaplastic astrocytoma also shows severe atypia and many mitotic figures but no pseudopalisading necrosis or microvascular proliferation. | Glioblastoma is a grade IV astrocytic tumor that is defined histologically be the four characteristics described above. It must be differentiated from ''anaplastic astrocytoma'', a grade III astrocytic tumor. Anaplastic astrocytoma also shows severe atypia and many mitotic figures but no pseudopalisading necrosis or microvascular proliferation. | ||
[[File:Glioblastoma - atypia.png|thumb|Tumor cells show severe atypia and there are many mitotic figures present. | [[File:Glioblastoma - atypia.png|thumb|Tumor cells show severe atypia and there are many mitotic figures present.|364x364px]] | ||
[[File:Glioblastoma - microvascular proliferation.png|thumb|Tumor on the left, showing microvascular proliferation. Normal brain parenchyme on the right for comparison.|346x346px]] | [[File:Glioblastoma - microvascular proliferation.png|thumb|Tumor on the left, showing microvascular proliferation. Normal brain parenchyme on the right for comparison.|346x346px]] | ||
[[Category:Pathology 2 - Histopathology slides]] | [[Category:Pathology 2 - Histopathology slides]] | ||