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Coagulation tests: Difference between revisions
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* Evaluate for [[DIC]] | * Evaluate for [[DIC]] | ||
* Evaluate for deficiency of coagulation factors I (fibrinogen), II (prothrombin), V, VIII, IX, X, XI, and XII | * Evaluate for deficiency of coagulation factors I (fibrinogen), II (prothrombin), V, VIII, IX, X, XI, and XII | ||
** This includes [[haemophilia]] A, B, and C, the congenital deficiency of factors VIII, IX, and XI, respectively | ** This includes [[haemophilia]] A, B, and C, the congenital deficiency of factors VIII, IX, and XI, respectively<section begin="physiology" /> | ||
<section begin="physiology" /> | |||
== Thrombin time == | == Thrombin time == | ||
The '''thrombin time''' evaluates the function of the common pathway alone, more specifically, the final step where [[fibrinogen]] is converted to fibrin. It's determined by adding thrombin to citrated plasma and measuring the time to clotting. It's mostly used to evaluate for fibrinogen disorders. | The '''thrombin time''' evaluates the function of the common pathway alone, more specifically, the final step where [[fibrinogen]] is converted to fibrin. It's determined by adding thrombin to citrated plasma and measuring the time to clotting. It's mostly used to evaluate for fibrinogen disorders. | ||