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The problem with prothrombin time is that the result varies significantly from lab to lab, depending on equipment and substrates used. As such, the prothrombin time is rarely evaluated alone, but the INR is used instead. | The problem with prothrombin time is that the result varies significantly from lab to lab, depending on equipment and substrates used. As such, the prothrombin time is rarely evaluated alone, but the INR is used instead. | ||
The '''international normalised ratio''' (INR) is a standardised form of prothrombin time which is normalised so that the result is similar between different laboratory methods and equipments. The prothrombin time is first measured and then normalised by a specific equation and factor. INR is generally used instead of prothrombin time for the same indications.<section end="physiology" /> | The '''international normalised ratio''' (INR) is a standardised form of prothrombin time which is normalised so that the result is similar between different laboratory methods and equipments. The prothrombin time is first measured and then normalised by a specific equation and factor. INR is generally used instead of prothrombin time for the same indications.<section end="physiology" /> | ||
Indications: | Indications: | ||