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Combined display of all available logs of greek.doctor. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 14:56, 30 May 2024 Nikolas talk contribs created page 42. Pre-analytical considerations of the hormone tests. (Created page with "* Measured by serum in plain tube (red) or gel tube (yellow) * Small peptide hormones ** Unstable, transported quickly and on ice ** TRH ** Renin * Amino acid derivatives ** T3, T4 *** Only free fraction is measured *** Protein binding influences measurement ** Adrenalin * Steroids ** Cortisol ** Aldosterone ** Sex hormones ** Both fractions are measured *** Binding protein should also be measured * Biological variation ** GH – pulsatile release ** Cortisol – influen...") Tag: Visual edit
- 21:01, 28 May 2024 Nikolas talk contribs created page File:Flag of Palestine.png
- 21:01, 28 May 2024 Nikolas talk contribs uploaded File:Flag of Palestine.png
- 10:16, 28 May 2024 Nikolas talk contribs created page 41. Laboratory tests of the cerebrospinal fluid and other body fluids. (Created page with "= Cerebrospinal fluid = {{#lst:cerebrospinal fluid|clinical biochemistry}} = Pleural fluid = {{#lst:Pleural effusion|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 09:52, 28 May 2024 Nikolas talk contribs created page Leukocyte count (Redirected page to Leukocyte#Leukocyte count (lab test)) Tags: New redirect Visual edit
- 09:52, 27 May 2024 Nikolas talk contribs created page Cerebrospinal fluid (Redirected page to Lumbar puncture) Tags: New redirect Visual edit
- 09:49, 27 May 2024 Nikolas talk contribs created page 40. Laboratory assessment of increased serum uric acid levels (Created page with "{{#lst:Uric acid|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 09:49, 27 May 2024 Nikolas talk contribs created page Uric acid (Created page with "<section begin="clinical biochemistry" />'''Uric acid''' (or '''urate''') is a metabolic breakdown product of purines. Purines are metabolised to xanthine and then to uric acid by xanthine oxidase. Deposition of uric acid crystals in joints is the driving mechanism in attacks of gout. Deposition of uric acid crystals in the kidney can cause uric acid nephropathy. Elevated uric acid is seen in gout, but is also seen in tumour lysis syndrome, ...") Tag: Visual edit: Switched
- 09:40, 27 May 2024 Nikolas talk contribs created page 39. Laboratory findings in proteinuria and haematuria (Created page with "= Proteinuria = {{#lst:Proteinuria|clinical biochemistry}} = Haematuria = {{#lst:Haematuria|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 17:29, 26 May 2024 Nikolas talk contribs created page Haematuria (Created page with "'''Haematuria''' refers to the presence of blood in the urine. We distinguish between microscopic haematuria or microhaematuria, when the concentration of blood is too low to be macroscopically visible, and macroscopic haematuria, or macrohaematuria (or gross haematuria), where the concentration is so high that the urine is visible coloured red. Haematuria is usually a sign of kidney or urinary tract pathology, including glomerulonephritis, urinary tract infection...") Tag: Visual edit
- 20:11, 24 May 2024 Nikolas talk contribs created page Proteinuria (Created page with "<section begin="clinical biochemistry" /><section begin="pathophysiology" />'''Proteinuria''' refers to pathological amounts of protein in the urine, defined as urinary protein content of > 150 mg per day. Physiologically, 50 - 150 mg protein is excreted in urine per day, most of which secreted by the tubuli with only small amounts filtered through the glomeruli. 99% of filtered proteins are reabsorbed in the tubuli. Most normal plasma proteins are not filtered in the g...") Tag: Visual edit: Switched
- 19:10, 24 May 2024 Nikolas talk contribs created page 38. Laboratory diagnosis and monitoring of chronic renal diseases (Created page with "{{#lst:Chronic kidney disease|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 19:07, 24 May 2024 Nikolas talk contribs created page 37. Laboratory diagnosis of acute renal diseases. (Created page with "= Kidney function tests = {{#lst:Kidney function tests|clinical biochemistry}} = Acute kidney injury = {{#lst:Acute kidney injury|clinical biochemistry}} = References =") Tag: Visual edit
- 11:53, 12 May 2024 Nikolas talk contribs created page Kidney function tests (Created page with "Several laboratory tests can be used to estimate the kidney function. These are important in the evaluation of chronic kidney disease (CKD) and acute kidney injury (AKI). The most common one is using the serum creatinine level to calculate the estimated glomerular filtration rate (eGFR). == Serum creatinine == Creatinine is a breakdown product of creatine phosphate following the creatine kinase reaction. It is eliminated by the kidneys by glome...") Tag: Visual edit: Switched
- 11:05, 12 May 2024 Nikolas talk contribs created page Creatinine (Created page with "'''Creatinine''' is a breakdown product of creatine phosphate following the creatine kinase reaction. Its significance in medicine is its use as a marker of kidney excretory function; more specifically, it's used to calculate the estimated glomerular filtration rate (eGFR), an estimate of the true glomerular filtration rate (GFR) when evaluating the kidney function. Creatinine and estimated glomarular filtration rate are extensively...") Tag: Visual edit
- 11:58, 8 May 2024 Nikolas talk contribs created page 36. Laboratory diagnosis and monitoring of malignant and inflammatory bowel diseases (Created page with "= Inflammatory bowel disease = {{#lst:Inflammatory bowel disease (Crohn disease and ulcerative colitis)|clinical biochemistry}} = Colorectal cancer = {{#lst:Colorectal cancer|clinical biochemistry}} = Malabsorption = {{#lst:Malabsorption syndromes|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 11:38, 8 May 2024 Nikolas talk contribs created page 35. Laboratory diagnosis of chronic pancreatitis (Created page with "{{#lst:Chronic pancreatitis|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 11:32, 8 May 2024 Nikolas talk contribs created page 34. Laboratory diagnosis of acute pancreatitis (Created page with "{{#lst:Acute pancreatitis|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 11:27, 8 May 2024 Nikolas talk contribs created page 33. Disorders of bilirubin metabolism (Created page with "{{#lst:Jaundice|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 11:26, 8 May 2024 Nikolas talk contribs created page Hyperbilirubinaemia (Redirected page to Jaundice) Tags: New redirect Visual edit
- 11:22, 8 May 2024 Nikolas talk contribs created page 32. Laboratory diagnostics of alcoholic liver damage. Laboratory tests to assess liver fibrosis (Created page with "= Alcoholic liver disease = {{#lst:Alcoholic liver disease|clinical biochemistry}} = Liver fibrosis and cirrhosis = {{#lst:Cirrhosis|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 11:10, 8 May 2024 Nikolas talk contribs created page ALT (Redirected page to Liver biochemical tests#Alanine aminotransferase (ALT)) Tags: New redirect Visual edit
- 11:10, 8 May 2024 Nikolas talk contribs created page AST (Redirected page to Liver biochemical tests#Aspartate aminotransferase (AST)) Tags: New redirect Visual edit
- 10:42, 8 May 2024 Nikolas talk contribs created page Prolactin (Created page with "<section begin="pathophysiology" />'''Prolactin''' is a hormone produced by the anterior pituitary in pregnancy, sleep, lactation, stress, physical exercise and hypoglycaemia. It stimulates the growth of glandular tissue in the breast and is necessary to produce milk. Prolactin inhibits FSH and LH. Dopamine usually inhibits the secretion of prolactin. TRH stimulates the production of prolactin. Pathologically elevated prolactin is called hyperprolactinaemia, and de...") Tag: Visual edit: Switched
- 10:42, 8 May 2024 Nikolas talk contribs created page Hyperprolactinaemia (Created page with "<section begin="pathophysiology" />'''Hyperprolactinaemia''' is the increased production of prolactin. It's a relatively rare disorder. == Etiology == hyperprolactinaemia occurs in: * Prolactinomas – prolactin-producing pituitary adenomas – most common cause * Damage to the hypothalamus and infundibular stalk – as this impairs the dopamine-mediated inhibition of prolactin * Hypothyroidism – as TRH stimulates prolactin * Dopamine antagonists * Chronic renal...") Tag: Visual edit: Switched
- 18:43, 1 May 2024 Nikolas talk contribs created page 31. Laboratory tests that predict hepatic disorders. (Created page with "{{:Liver biochemical tests}}") Tag: Visual edit
- 18:43, 1 May 2024 Nikolas talk contribs created page Liver biochemical tests (Created page with "Several '''liver biochemical tests''' can be used to evaluate the state of the liver. These are also called '''liver function tests (LFTs)''', but this is sort of misleading because the tests do not necessarily reveal how the liver is functioning. {| class="wikitable" !'''Parameter''' !'''Sample''' !'''Reference range''' |- !Total bilirubin |Serum |5 – 20 µM |- !Albumin |Serum |35 – 53 g/L |- !Total protein |Serum |66 – 83 g/L |- !AST |Serum |< 44 U/L |- !ALT |Ser...") Tag: Visual edit: Switched
- 18:25, 1 May 2024 Nikolas talk contribs created page Cholecystitis (Created page with "{{:Stub}} '''Cholecystitis''' refers to inflammation of the gallbladder. The most common type is acute calculous cholecystitis. Category:Gastrointestinal surgery") Tag: Visual edit
- 18:07, 1 May 2024 Nikolas talk contribs created page Liver function tests (Redirected page to Liver biochemical tests) Tags: New redirect Visual edit
- 18:06, 1 May 2024 Nikolas talk contribs created page 30. Lipids and lipoproteins in the blood plasma (Created page with "{| class="wikitable" !'''Parameter''' !'''Sample''' !'''Reference range''' |- !Cholesterol |Serum |4,0 – 5,6 mM |- !LDL |Serum |0,0 – 3,4 mM |- !HDL |Serum |0,9 – 1,7 mM |} * Analysis of lipids ** Enzymatic assay *** Cholesterol *** HDL, LDL *** <abbr>FFA</abbr> *** Triglycerides ** Immunoassay *** ApoA1 *** ApoB *** Lp(a) ** Lipoprotein electrophoresis ** Ultracentrifugation – sorted after density * Cholesterol ** Component of cell membrane ** Precursor of ster...") Tag: Visual edit
- 18:02, 1 May 2024 Nikolas talk contribs created page 29. Clinical biochemistry of hypoglycaemia and hyperglycaemia (Created page with "= Hypoglycaemia = {{#lst:Hypoglycaemia|clinical biochemistry}} = Hyperglycaemia = {{#lst:Hyperglycaemia|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 18:01, 1 May 2024 Nikolas talk contribs created page Hyperglycaemia (Created page with "<section begin="clinical biochemistry" />'''Hyperglycaemia''' refers to higher-than-normal blood glucose level. The upper limit of "normal" glucose level depends on whether there is fasting or not. When fasting, the upper normal level is 7.0 mM. Chronic hyperglycaemia is a defining feature of diabetes mellitus.<section end="clinical biochemistry" /> Category:Pathophysiology") Tag: Visual edit: Switched
- 17:58, 1 May 2024 Nikolas talk contribs created page Hypoglycaemia (Created page with "<section begin="clinical biochemistry" />'''Hypoglycaemia''' is defined as a serum glucose level below 3.5 mmol/L. It most frequently occurs in diabetics in association with taking too much insulin or other antidiabetic (glucose-lowering) drugs. It may also occur in chronic alcoholics. Rare causes include beta blockers and insulinomas. It’s most characteristic for type 1 diabetics.<section end="clinical biochemi...") Tag: Visual edit
- 17:45, 1 May 2024 Nikolas talk contribs created page 28. Diagnostic criteria of diabetes mellitus (WHO criteria). Laboratory monitoring of patients with diabetic history (Created page with "{{#lst:Diabetes mellitus|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 17:33, 1 May 2024 Nikolas talk contribs created page Coronary heart disease (Redirected page to Ischaemic heart disease) Tags: New redirect Visual edit
- 09:20, 1 May 2024 Nikolas talk contribs created page Diabetes mellitus (Created page with "'''Diabetes mellitus''' (DM) is a group of disorders characterised by chronic hyperglycaemia due to abnormal carbohydrate metabolism. There are many types, but the most common types are type 1 diabetes mellitus and type 2 diabetes mellitus. DM is a very common disease, and the most common form, type 2, is associated with inactivity and obesity, which are increasing globally. Chronic hyperglycaemia causes severe long-term and short-term complications which may...") Tag: Visual edit
- 09:07, 1 May 2024 Nikolas talk contribs created page 27. Laboratory diagnostics of the striated muscle diseases. (Created page with "= Creatine kinase = {{#lst:Creatine kinase|clinical biochemistry}} = Other = * LDH is elevated in any form of cell injury, including muscle injury * Duchenne muscle dystrophy ** Elevated total creatine kinase ** Creatine in urine * Rhabdomyolysis ** Elevated total creatine kinase (very high levels, 5x upper limit) ** Elevated myoglobin ** Elevated LDH, K+, phosphate ** Myoglobinuria – orange or brown ** Renal impairment parameters *** Urea *** Electrolytes [...") Tag: Visual edit
- 09:03, 1 May 2024 Nikolas talk contribs created page Creatine kinase (Created page with "<section begin="clinical biochemistry" />'''Creatine kinase''' (CK) is an enzyme which catalyses the formation of creatine phosphate from creatine. Creatine phosphate is the main energy source in muscle, and so this enzyme is abundant in skeletal muscle. There are three isotypes of CK. CK-MM is mostly found in skeletal muscle. CK-MB is mostly found in myocardium (but only accounts for 30% of CK here). CK-BB is the dominant form in smooth muscle. == As a laboratory mark...") Tag: Visual edit: Switched
- 08:55, 1 May 2024 Nikolas talk contribs created page 26. Laboratory monitoring the therapy of myocardial infarction. Laboratory approaches in chronic heart failure (BNP, proBNP, electrolytes). (Created page with "= Monitoring therapy of AMI = * Decrease in troponin after treatment -> treatment successful * High troponin -> Worse prognosis * Immediately following reperfusion, troponin may temporarily increase = Heart failure = {{#lst:Heart failure|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 14:16, 28 April 2024 Nikolas talk contribs created page 25. Current analytical protocol to detect acute myocardial infarction; international recommendations. (Created page with "{{#lst:Acute coronary syndrome|clinical biochemistry}} == References == <references /> Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 13:05, 28 April 2024 Nikolas talk contribs created page 24. Laboratory monitoring of anticoagulant therapies. (Created page with "= Warfarin = {{#lst:Vitamin K antagonists|clinical biochemistry}} = Heparin = {{#lst:Unfractionated heparin|clinical biochemistry}} = LMWH = {{#lst:Low-molecular-weight heparin|clinical biochemistry}} = DOAC = {{#lst:Direct oral anticoagulants|clinical biochemistry}} = Antiplatelets = {{#lst:Acetylsalicylic acid|clinical biochemistry}} {{#lst:P2Y12 inhibitors|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)") Tag: Visual edit
- 12:39, 28 April 2024 Nikolas talk contribs created page Dipyridamole (Created page with "'''Dipyridamole''' is an antiplatelet drug. It's rarely used, but may be indicated for the prevention of ischaemic stroke. It's often combined with acetylsalicylic acid. It's a phosphodiesterase inhibitor. It increases the amount of cAMP in the platelets, which inhibits platelet aggregation. Dipyridamole is also a pharmacological "stressor", and can therefore be used to simulate physical stress in case of stress myocardial perfusion i...") Tag: Visual edit: Switched
- 12:34, 28 April 2024 Nikolas talk contribs created page Glycoprotein IIb/IIIa inhibitors (Created page with "'''Glycoprotein IIb/IIIa inhibitors''' are antiplatelets. They are mostly used for short-term treatment before and during percutaneous coronary intervention. They are administered by i.v. injection, == Compounds == * Abciximab * Eptifibatide * Tirofiban == Mechanism of action == These drugs bind to and inhibit the receptors glycoprotein IIb/IIIa, which prevents platelets from binding to each other and therefore preventing aggregation.<noinclude>Category:Pharmaco...") Tag: Visual edit: Switched
- 12:32, 28 April 2024 Nikolas talk contribs created page P2Y12 inhibitors (Created page with "'''P2Y<sub>12</sub> inhibitors''' are antiplatelet drugs. They are are often used in combination with acetylsalicylic acid, which is called ''dual antiplatelet therapy'' (<abbr>DAPT</abbr>). However, they may also be used alone. == Compounds == * Clopidogrel (Plavix®) * Prasugrel (Efient®) * Ticagrelor (Brilique®) == Mechanism of action == These drugs inhibit the P2Y12 receptor, an ADP receptor which is found on platelets. This receptor binds ADP which is r...") Tag: Visual edit: Switched
- 12:28, 28 April 2024 Nikolas talk contribs created page Acetylsalicylic acid (Created page with "{{:Stub}} '''Acetylsalicylic acid''' (ASA) is technically an NSAID, although it’s more frequently used as an antiplatelet rather than for its anti-inflammatory effects. It’s a very frequently used antiplatelet. ASA is given in much lower dose for use as an antiplatelet drug than when used as an anti-inflammatory. Antiplatelet dose is 50 – 150 mg/day and in an extended-release formulation (Albyl-E®) while anti-inflammatory dose is 500 m...") Tag: Visual edit: Switched
- 12:26, 28 April 2024 Nikolas talk contribs created page Antiplatelet drugs (Created page with "'''Antiplatelet drugs''' are drugs which treat and prevent thrombosis by targeting the platelet's role in the coagulation cascade, thereby reducing the blood's tendency to form thrombi. As with anticoagulants, antiplatelets are also widely used in medicine (mostly cardiology and vascular surgery). Many patients are on antiplatelets. Unlike anticoagulants, antiplatelet drugs can be combined. When there is vascular damage, receptors on the surface of platelet...") Tag: Visual edit: Switched
- 12:05, 28 April 2024 Nikolas talk contribs created page Anticoagulants (Redirected page to Anticoagulant) Tags: New redirect Visual edit
- 12:04, 28 April 2024 Nikolas talk contribs created page Low-molecular-weight heparin (Created page with "<section begin="clinical biochemistry" />The '''low-molecular-weight heparins''' (LMWH) are ''fractionated heparins'' as opposed to unfractionated heparin. These drugs are just fragments of the unfractionated heparin. They’re more predictable and have longer half-life than unfractionated heparin and are therefore preferred in most cases.<section end="clinical biochemistry" /> The LMWHs have a molecular weight of 3 – 4 kDa. == Compounds == * Enoxaparin (Clexane...") Tag: Visual edit: Switched
- 11:55, 28 April 2024 Nikolas talk contribs created page APTT (Redirected page to Coagulation tests#Activated partial thromboplastin time (aPTT)) Tags: New redirect Visual edit
- 11:52, 28 April 2024 Nikolas talk contribs created page International normalised ratio (Redirected page to Coagulation tests#Prothrombin time and international normalised ratio (INR)) Tags: New redirect Visual edit
