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12:29, 10 January 2023 Nikolas talk contribs created page AMPK pathway (Created page with "center|frameless|560x560px center|frameless|682x682px Category:Biochemistry help material") Tag: Visual edit
12:29, 10 January 2023 Nikolas talk contribs created page File:AMPK pathway 2.png
12:29, 10 January 2023 Nikolas talk contribs uploaded File:AMPK pathway 2.png
12:28, 10 January 2023 Nikolas talk contribs created page File:AMPK pathway 1.png
12:28, 10 January 2023 Nikolas talk contribs uploaded File:AMPK pathway 1.png
12:28, 10 January 2023 Nikolas talk contribs created page Glucagon pathway (Redirected page to Protein Kinase A pathway) Tags: New redirect Visual edit
12:28, 10 January 2023 Nikolas talk contribs created page Protein Kinase A pathway (Created page with "Protein kinase A (PKA) is the major downstream effector of many hormones, including glucagon, epinephrine, vasopressin, and neurotransmitters. The figure below shows multiple actions of PKA, but note that no single hormone effectuates all these changes. Glucagon and epinephrine mediate most of them. The effect of <abbr>PKA</abbr> on Aquaporin 2 and K+-channel is ''not'' activated by glucagon or epinephrine, but by vasopressin and neurotransmitters, respectively! File:P...") Tag: Visual edit
12:24, 10 January 2023 Nikolas talk contribs created page File:Protein kinase A pathway.png
12:24, 10 January 2023 Nikolas talk contribs uploaded File:Protein kinase A pathway.png
12:23, 10 January 2023 Nikolas talk contribs created page Insulin pathway (Created page with "frameless|671x671px {| class="wikitable" !Abbreviation !Name !Function |- |PDE |Phosphodiesterase |Degrade cAMP to 5′-AMP which inhibits <abbr>PKA</abbr> and therefore the effect of glucagon and epinephrine |- |IRS |Insulin receptor substrate |Activates MAPK and PDE |- |<abbr>PKB</abbr>/Akt |Protein kinase B (or Akt) |Activated by PDK1, mediates many of the insulin functions. |- |MAPK |MAP kinase |Activate a protein cascade called the MAP k...") Tag: Visual edit
12:22, 10 January 2023 Nikolas talk contribs created page File:Insulin pathway.png
12:22, 10 January 2023 Nikolas talk contribs uploaded File:Insulin pathway.png
12:21, 10 January 2023 Nikolas talk contribs created page Hexokinase and glucokinase (Created page with "Hexokinase is an enzyme which catalyzes the phosphorylation of glucose into glucose 6-phosphate. There are multiple forms, from I to IV. Hexokinase IV is also called glucokinase. Glucokinase (hexokinase IV) differs from the other three types of hexokinase (hexokinase I, II and III) in multiple ways. They’re summarized in the table below. {| class="wikitable" !Property !Hexokinase (I, II, III) !Glucokinase (hexokinase IV) |- |Concentration of glucose where enzyme is ha...") Tag: Visual edit
12:21, 10 January 2023 Nikolas talk contribs created page File:Glucokinase in beta cells.png
12:21, 10 January 2023 Nikolas talk contribs uploaded File:Glucokinase in beta cells.png
12:20, 10 January 2023 Nikolas talk contribs created page File:Hexokinase I and IV activity.png
12:20, 10 January 2023 Nikolas talk contribs uploaded File:Hexokinase I and IV activity.png
14:51, 5 January 2023 Nikolas talk contribs created page How to calculate ATP yield (Created page with "Many different compounds in the body can be broken down to yield ATP. There is almost always a question on the exam where you need to calculate the ATP yield of a certain compound. You must write the process of your calculation on the exam. Here are some examples of compounds: * Fatty acids ** Hexanoyl-CoA ** Hexanoate (hexanoyl-CoA without the -CoA) ** Octanoyl-CoA (an 8 carbon long fatty acid) * Ketone bodies ** β-hydroxybutyrate ** Acetoacetate ** Acetoacetyl-CoA *...") Tag: Visual edit
14:51, 5 January 2023 Nikolas talk contribs created page Enzymes and regulation (Created page with "=== General rules about regulation: === * Hormones always regulate stuff indirectly * Hormones almost always regulate stuff covalently * Kinases or phosphatases almost always regulate stuff covalently * Something that’s not a protein can never regulate anything covalently directly The ones I think are most important are ''italicised''. Most of them are taken from Lehninger 6th edition. The “Page” column shows which page from the book has been used as a source....") Tag: Visual edit
14:33, 5 January 2023 Nikolas talk contribs created page Diseases in biochemistry 1 (Created page with "{| class="wikitable" |'''Disease''' |'''Affected enzyme(s)''' |- |Alkaptonuria |Homogentisate 1,2-dioxygenase |- |Fructosemia |Fructose 1-phosphate aldolase |- |Fructosuria |Fructokinase |- |Phenylketonuria |Phenylalanine hydroxylase |- |Maple syrup urine disease |Branched-chain α-ketoacid dehydrogenase complex |- |Tyrosinemia type I |Fumarylacetoacetase |- |Tyrosinemia type II |Tyrosine aminotransferase |- |Tyorsinemia type III |p-hydroxyphenylpyruvate dioxygenase |- |...") Tag: Visual edit
14:30, 5 January 2023 Nikolas talk contribs created page How to pass biochemistry 1 (Created page with "You should know the MRTs very well (use flashcards), and also know what reaction is impaired in a few diseases. You can be asked questions about the smallest things, and some questions can be so vague you’re not even sure what they’re asking. You should always ask teachers to clarify questions you don’t understand. However, if you know the MRTs well, and know most of what’s written here, you should at least pass. In some topics, you might only need to know the su...") Tag: Visual edit
14:30, 5 January 2023 Nikolas talk contribs created page Category:Biochemistry 1 lectures (Created page with "Category:Biochemistry 1") Tag: Visual edit
14:29, 5 January 2023 Nikolas talk contribs created page Category:Biochemistry help material (Created page with "Category:Biochemistry 1") Tag: Visual edit
14:29, 5 January 2023 Nikolas talk contribs created page Category:Biochemistry 1 (Created page with "Category:2nd year") Tag: Visual edit
14:23, 5 January 2023 Nikolas talk contribs created page 76. Reabsorption and secretion of different substances in the renal tubule. Methods for their investigation (Created page with "thumb|This figure shows the different parts of the tubular system and which substances are secreted and reabsorbed and where. From Wikipedia. The glomerular filtration rate is approx. 100 mL/min, which equals approx. 180 litres per day. With 180 litres of plasma being filtered into the Bowman space every day you’d expect us to urinate 180L every day. However, we only produce approx. 1,5L of urine every day, and not 180L. The difference of 17...") Tag: Visual edit
14:18, 5 January 2023 Nikolas talk contribs created page File:Tubular system.gif
14:18, 5 January 2023 Nikolas talk contribs uploaded File:Tubular system.gif
14:16, 5 January 2023 Nikolas talk contribs created page 75. Regulation of renal blood flow and pressure. Renin-angiotensin system (Created page with "== Regulation of renal blood flow == The <abbr>GFR</abbr> is proportional to the renal blood flow. If the renal blood flow were not autoregulated a 25% increase in blood pressure would increase the GFR by the same amount. This would increase the amount of urine produced ''30-fold''. To prevent this, the renal blood flow is autoregulated. The renal blood flow is autoregulated as long as the MAP is between 80 and 200 mmHg. This ensures that the RBF and therefore the GFR i...") Tag: Visual edit
14:14, 5 January 2023 Nikolas talk contribs created page 74. Renal blood flow. Clearance of PAH. Extraction ratio. Filtration fraction (Created page with "== Renal blood and plasma flow == The kidneys receive large amounts of blood flow every minute. This allows the kidneys to filter large amounts of blood every minute. The renal blood flow (RBF) is normally 1200 mL/min, a whopping 20% of the cardiac output. The kidneys receive so much blood flow because they should filter as much blood as possible, not because the kidneys have a large oxygen requirement. In cases where blood flow is needed elsewhere, like during exercise...") Tag: Visual edit
14:13, 5 January 2023 Nikolas talk contribs created page File:Extraction ratio.png
14:13, 5 January 2023 Nikolas talk contribs uploaded File:Extraction ratio.png
14:12, 5 January 2023 Nikolas talk contribs created page 73. Dynamics of glomerular filtration. Glomerular filtration rate. Plasma clearance (Created page with "== Kidneys == === Functions: === The kidneys have many functions. Their major function is to filter the plasma for waste products. Here are all of the kidney’s functions: * Excretory functions ** Excretion of waste products *** Urea *** Creatinine ** Excretion of toxins ** Excretion of certain drugs * Regulation of fluid and electrolyte balance ** Regulation of the fluid volume ** Keeping the plasma isotonic ** Maintaining isoosmolarity ** Regulating pH * Synthesis o...") Tag: Visual edit
14:10, 5 January 2023 Nikolas talk contribs created page File:GFR with PAH.png
14:10, 5 January 2023 Nikolas talk contribs uploaded File:GFR with PAH.png
14:10, 5 January 2023 Nikolas talk contribs created page File:GFR with inulin.png
14:10, 5 January 2023 Nikolas talk contribs uploaded File:GFR with inulin.png
14:08, 5 January 2023 Nikolas talk contribs created page File:Nephron substances.png
14:08, 5 January 2023 Nikolas talk contribs uploaded File:Nephron substances.png
14:07, 5 January 2023 Nikolas talk contribs created page File:Clearance formula.png
14:07, 5 January 2023 Nikolas talk contribs uploaded File:Clearance formula.png
14:06, 5 January 2023 Nikolas talk contribs created page File:GFR from EFP.png
14:06, 5 January 2023 Nikolas talk contribs uploaded File:GFR from EFP.png
14:05, 5 January 2023 Nikolas talk contribs created page File:Ultrafiltration.png
14:05, 5 January 2023 Nikolas talk contribs uploaded File:Ultrafiltration.png
14:05, 5 January 2023 Nikolas talk contribs created page File:Starling equation kidney.png
14:05, 5 January 2023 Nikolas talk contribs uploaded File:Starling equation kidney.png
14:03, 5 January 2023 Nikolas talk contribs created page File:Glomerular tuft.jpg
14:03, 5 January 2023 Nikolas talk contribs uploaded File:Glomerular tuft.jpg
14:02, 5 January 2023 Nikolas talk contribs created page File:Nephron.png
14:02, 5 January 2023 Nikolas talk contribs uploaded File:Nephron.png