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Squamous cell carcinoma of the skin: Difference between revisions

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(Created page with "<section begin="dermatology" /> * Second most common skin cancer * Risk factors ** Chronic sun exposure ** Precancerous lesions *** Actinic keratosis *** Bowen disease (SCC in situ) *** Leukoplakia ** Radiation ** Chronic scars, ulcers ** Arsenic, tar * Clinical features ** Painless, non-healing, bleeding ulcer or nodule ** Rapid growing ** On sun-exposed areas *** Face and neck *** Lower lip * Prognosis ** 5% risk of metastasis * Diagnosis ** Punch biopsy * Treatment **...")
 
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<section begin="dermatology" />
<section begin="dermatology" /><section begin="oncology" />
* Second most common skin cancer
* Epidemiology
** SCC accounts for 18% of all skin cancer
** Second most common skin cancer, after BCC
* Risk factors
* Risk factors
** Chronic sun exposure
** Chronic sun exposure
** Transplantation (transplant-related immunosuppression increases the risk 65-fold)
** Precancerous lesions
** Precancerous lesions
*** Actinic keratosis
*** Actinic keratosis
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*** Lower lip
*** Lower lip
* Prognosis
* Prognosis
** 5% risk of metastasis
** Low risk of metastasis (5%)
** Worse prognosis in transplant patients
* Diagnosis
* Diagnosis
** Punch biopsy
** Punch biopsy or after surgical excision
* Treatment
* Treatment
** Surgical excision with 5 mm safety border
** Surgery
** Radiation therapy
*** Surgical excision with 5 mm safety border
*** Primary treatment is almost all cases
** Radiotherapy
*** If surgery is not an option
*** As adjuvant therapy if high-risk features are discovered during pathological staging
** Immune therapy
*** For advanced SCC
*** Cemiplimab – anti-PD-1
** Alternatives for superficial and small SCCs
*** Cryosurgery
** Mohs micrographic surgery
** Mohs micrographic surgery
** For low-risk, small
** For low-risk, small SCC
*** Cryotherapy
*** Cryotherapy
*** Curettage
*** Curettage
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** Abdominal US
** Abdominal US
** Sun protection
** Sun protection
<section end="dermatology" />
<section end="dermatology" /><section end="oncology" />
[[Category:Dermatology]]
[[Category:Dermatology]]