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(Created page with "* Polychemotherapy = simultaneous use of multiple chemo drugs ** The term is not consistently used, even by me ** Recently, we have moved to preferring to use multiple chemo drugs, so the term is kind of reduntant * Mode of actions ** Induce DNA damage ** Inhibit DNA repair mechanisms ** Inhibit metabolism *** For example nucleotide synthesis ** Inhibit mitosis ** Inhibit neo-vascularization * Commonly used drugs ** Platinum-based drugs *** Cisplatin **** Very nephrotoxi...") |
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