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47. Bullous pemphigoid: Difference between revisions
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(Created page with "'''Staining''': HE '''Organ''': Skin '''Description''': Bullous pemphigoid is characterized by subepidermal nonancantholytic blisters. The main finding here is that the epidermis has been separated from the basement membrane it is usually attached to. This forms a bulla between the epidermis and the basement membrane. This bulla is filled with low-protein fluid and eosinophils. '''Diagnosis''': Bullous pemphigoid '''Causes''': * Unknown '''Theory''': Blisters in...") |
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'''Staining''': HE | [[File:Bullous pemphigoid - overview.png|thumb|Overview]]'''Staining''': HE | ||
'''Organ''': Skin | '''Organ''': Skin | ||
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Bullous pemphigoid is characterized by subepidermal nonancantholytic blisters. The main finding here is that the epidermis has been separated from the basement membrane it is usually attached to. This forms a bulla between the epidermis and the basement membrane. This bulla is filled with low-protein fluid and eosinophils. | Bullous pemphigoid is characterized by subepidermal nonancantholytic blisters. The main finding here is that the epidermis has been separated from the basement membrane it is usually attached to. This forms a bulla between the epidermis and the basement membrane. This bulla is filled with low-protein fluid and eosinophils. | ||
'''Diagnosis''': Bullous pemphigoid | '''Diagnosis''': Bullous pemphigoid[[File:Bullous pemphigoid - high magnification.png|thumb|High magnification picture]]'''Causes''': | ||
'''Causes''': | |||
* Unknown | * Unknown | ||
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Bullous pemhpigoid and pemphgoid vulgaris share a similar pathogenic mechanism, but differ in clinical representation due to variation in the antigen targeted. Hemidesmosomes in bullous pemphigoid and desmosomes in pemhigus vulgaris. | Bullous pemhpigoid and pemphgoid vulgaris share a similar pathogenic mechanism, but differ in clinical representation due to variation in the antigen targeted. Hemidesmosomes in bullous pemphigoid and desmosomes in pemhigus vulgaris. | ||
[[Category:Pathology 2 - Histopathology slides]] | [[Category:Pathology 2 - Histopathology slides]] | ||