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45. Nodular melanoma: Difference between revisions
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(Created page with "'''Staining''': HE '''Organ''': Skin '''Description''': Like the name implies the tumor forms a nodule. The tumor cells are highly atypical, bordering on anaplastic. Some of the tumor cells contain melanin. Tumor cells are present in the epidermis as well. '''Diagnosis''': Nodular melanoma '''Causes''': * Sun exposure '''Theory''': The presence of tumor cells in the epidermis is essential to establish the diagnosis of ''primary'' melanoma. If there were no tumor...") |
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'''Staining''': HE | [[File:Nodular melanoma - overview.png|thumb|Overview|376x376px]]'''Staining''': HE | ||
'''Organ''': Skin | '''Organ''': Skin | ||
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* Sun exposure | * Sun exposure | ||
[[File:Nodular melanoma - melanin.png|thumb|Tumour cells containing melanin]]'''Theory''': | |||
'''Theory''': | |||
The presence of tumor cells in the epidermis is essential to establish the diagnosis of ''primary'' melanoma. If there were no tumor cells there the lesion could have been a melanoma metastasis rather than the primary tumor. | The presence of tumor cells in the epidermis is essential to establish the diagnosis of ''primary'' melanoma. If there were no tumor cells there the lesion could have been a melanoma metastasis rather than the primary tumor. | ||
[[File:Nodular melanoma - atypia.png|thumb|Severe atypia, or even anaplasia|left]] | |||
[[File:Nodular melanoma - epidermis.png|thumb|Tumour cells in the epidermis]] | |||
[[File:Nodular melanoma - atypia.png | |||
[[File:Nodular melanoma - epidermis.png | |||
[[Category:Pathology 2 - Histopathology slides]] | [[Category:Pathology 2 - Histopathology slides]] | ||