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17. CLL or SLL infiltration in lymph node: Difference between revisions
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'''Staining''': HE | [[File:CLL - overview.png|thumb|Overview. No follicles, no cortex, no medulla, no sinuses.|407x407px]]'''Staining''': HE | ||
'''Organ''': Lymph node | '''Organ''': Lymph node | ||
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It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore ''centrocytic'' or ''centrocytoid.'' | It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore ''centrocytic'' or ''centrocytoid.'' | ||
'''Diagnosis:''' Small lymphocytic lymphoma (or chronic lymphocytic leukaemia) | '''Diagnosis:''' Small lymphocytic lymphoma (or chronic lymphocytic leukaemia)[[File:CLL - high magnification.png|thumb|Nice-looking cells.|398x398px]]'''Risk factors:''' Not well known | ||
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'''Theory:''' | '''Theory:''' | ||
CLL/SLL is the most frequent adult leukaemia. Because this slide shows affection of a lymph node, this is most likely SLL (although it could be CLL with lymph node affection as well). | CLL/SLL is the most frequent adult leukaemia. Because this slide shows affection of a lymph node, this is most likely SLL (although it could be CLL with lymph node affection as well). | ||
[[Category:Pathology 2 - Histopathology slides]] | [[Category:Pathology 2 - Histopathology slides]] | ||