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* Marsh 3 – Intraepithelial lymphocytosis, crypt hyperplasia and villous atrophy are seen | * Marsh 3 – Intraepithelial lymphocytosis, crypt hyperplasia and villous atrophy are seen | ||
In addition to this is Marsh 3 divided into a, b and c subtypes depending on the severity of the villous atrophy, where c is total villous atrophy. In this slide are areas where there are no evidence of villi, so it’s Marsh 3c. | In addition to this is Marsh 3 divided into a, b and c subtypes depending on the severity of the villous atrophy, where c is total villous atrophy. In this slide are areas where there are no evidence of villi, so it’s Marsh 3c. ''The Marsh classification originally had a Marsh 4 as well, which included hypoplasia of the small bowel architecture, but the original classification has been revised to only go from 1 – 3.'' The number of intestinal crypts (of Lieberkühn) is normally low in the duodenum, however here can we see that crypts are plenty. | ||
''The Marsh classification originally had a Marsh 4 as well, which included hypoplasia of the small bowel architecture, but the original classification has been revised to only go from 1 – 3.'' | |||
The number of intestinal crypts (of Lieberkühn) is normally low in the duodenum, however here can we see that crypts are plenty. | |||
[[Category:Pathology 2 - Histopathology slides]] | [[Category:Pathology 2 - Histopathology slides]] |