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34. Cervical intraepithelial neoplasia CIN III: Difference between revisions

34. Cervical intraepithelial neoplasia CIN III (view source)

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The cells with the perinuclear halo and irregular nuclei are called koilocytes, which are a sign of HPV infection. The presence of these cells is called koilocytosis or koilocytic atypia.[[File:CIN III pleiomorphism.png|thumb|Note also that the cells are pleiomorphic.|left]]
The cells with the perinuclear halo and irregular nuclei are called koilocytes, which are a sign of HPV infection. The presence of these cells is called koilocytosis or koilocytic atypia.[[File:CIN III pleiomorphism.png|thumb|Note also that the cells are pleiomorphic.|left]]


This dysplasia is part of a condition called cervical intraepithelial neoplasia (CIN). This condition has three degrees of severity: CIN I – Dysplasia in only lower 1/3 of epithelium, CIN II – Dysplasia in lower 2/3 of epithelium, and CIN III – Dysplasia in the whole epithelium. CIN is a precancerous lesion for cervical cancer. CIN III is the closest to becoming cancer while CIN I is the earliest stage. However, not all CIN III lesions become cancer – only 10% of them become cancerous. Because dysplasia is in the whole width of the epithelium in this slide it is classified as CIN III.
For the types of cervical intraepithelial neoplasia (CIN), see the theory topic. Because dysplasia is in the whole width of the epithelium in this slide it is classified as CIN III.
[[Category:Pathology 1 - Histopathology slides]]
[[Category:Pathology 1 - Histopathology slides]]