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49. Microcellular carcinoma of the lung: Difference between revisions

49. Microcellular carcinoma of the lung (view source)

Revision as of 12:49, 5 July 2024

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(Created page with "'''Staining''': HE '''Organ''': Lung '''Description''': We can see some normal lung parenchyme that has been invaded by multiple foci. There is also a large tumor on the left of the slide. The cells of the tumor are very small, and the tumor forms no structure. Some areas show cell with nuclei that “mold” into each other. Many mitotic figures are visible. The chromatin of the tumor cells is granular, making it look like salt and pepper. '''Diagnosis''': Small...")
 
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'''Staining''': HE
[[File:Small cell lung cancer overview.png|thumb|Overview of the slide]]'''Staining''': HE


'''Organ''': Lung
'''Organ''': Lung
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Many mitotic figures are visible.
Many mitotic figures are visible.


The chromatin of the tumor cells is granular, making it look like salt and pepper.
The chromatin of the tumor cells is granular, making it look like salt and pepper.[[File:Small cell lung cancer tumour cells.png|thumb|Close-up of the tumor. Note that the cells don’t form any structures (glands, layers). They just exist next to each other.]]'''Diagnosis''': Small-cell lung carcinoma
 
'''Diagnosis''': Small-cell lung carcinoma


'''Causes''':
'''Causes''':
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A small-cell carcinoma is a type III neuroendocrine tumor. The salt-n-pepper morphology is characteristic for neuroendocrine tumors.
A small-cell carcinoma is a type III neuroendocrine tumor. The salt-n-pepper morphology is characteristic for neuroendocrine tumors.
[[File:Small cell lung cancer overview.png|center|thumb|Overview of the slide]]
[[File:Small cell lung cancer nuclear moulding.png|thumb|Nuclear moulding. Note the small size of the tumor cells. Note also their pleomorphism (anisochromasia, anisonucleosis, anisocytosis).|left]]
[[File:Small cell lung cancer tumour cells.png|center|thumb|Close-up of the tumor. Note that the cells don’t form any structures (glands, layers). They just exist next to each other.]]
[[File:Small cell lung cancer mitosis.png|thumb|This poor cell was in the middle of dividing when it died.]]
[[File:Small cell lung cancer nuclear moulding.png|center|thumb|Nuclear moulding. Note the small size of the tumor cells. Note also their pleomorphism (anisochromasia, anisonucleosis, anisocytosis).]]
[[File:Small cell lung cancer mitosis.png|center|thumb|This poor cell was in the middle of dividing when it died.]]
[[Category:Pathology 1 - Histopathology slides]]
[[Category:Pathology 1 - Histopathology slides]]