Jump to content

34. Cervical intraepithelial neoplasia CIN III: Difference between revisions

34. Cervical intraepithelial neoplasia CIN III (view source)

Revision as of 12:15, 5 July 2024

14 bytes removed ,  5 July
no edit summary
VisualWikitext
No edit summary
Tags: Manual revert Visual edit
No edit summary
Line 7: Line 7:
The PAS-negative epithelium contains pleomorphic cells (they have different shapes and sizes). These cells are larger than the PAS-positive cells as well. We can also see some cells undergoing mitosis here. A special cell type with a white “ring” around an irregular nucleus can be seen.
The PAS-negative epithelium contains pleomorphic cells (they have different shapes and sizes). These cells are larger than the PAS-positive cells as well. We can also see some cells undergoing mitosis here. A special cell type with a white “ring” around an irregular nucleus can be seen.


'''Diagnosis''': Cervical intraepithelial neoplasia CIN III[[File:CIN III dysplasia transition.png|thumb|This picture shows the abrupt change from healthy, PAS-positive to PAS-negative epithelium.|264x264px]]'''Causes''': Human papilloma virus (<abbr>HPV)</abbr> infection
'''Diagnosis''': Cervical intraepithelial neoplasia CIN III[[File:CIN III dysplasia transition.png|thumb|Note the abrupt change from healthy, PAS-positive to PAS-negative epithelium.|264x264px]]'''Causes''': Human papilloma virus (<abbr>HPV)</abbr> infection


'''Theory''': The normal epithelium here is the PAS-positive epithelium. The PAS positivity comes from the large amount of glycogen in the epithelial cells. Because the epithelium is stratified squamous and not columnar we know this section is from the exocervix.
'''Theory''': The normal epithelium here is the PAS-positive epithelium. The PAS positivity comes from the large amount of glycogen in the epithelial cells. Because the epithelium is stratified squamous and not columnar we know this section is from the exocervix.