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34. Cervical intraepithelial neoplasia CIN III: Difference between revisions

34. Cervical intraepithelial neoplasia CIN III (view source)

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The cells with the perinuclear halo and irregular nuclei are called koilocytes, which are a sign of HPV infection. The presence of these cells is called koilocytosis or koilocytic atypia.[[File:CIN III pleiomorphism.png|thumb|Note also that the cells are pleiomorphic.|left]]
The cells with the perinuclear halo and irregular nuclei are called koilocytes, which are a sign of HPV infection. The presence of these cells is called koilocytosis or koilocytic atypia.[[File:CIN III pleiomorphism.png|thumb|Note also that the cells are pleiomorphic.|left]]


This dysplasia is part of a condition called cervical intraepithelial neoplasia (CIN). This condition has three degrees of severity: CIN I – Dysplasia in only lower 1/3 of epithelium, CIN II – Dysplasia in lower 2/3 of epithelium, and CIN III – Dysplasia in the whole epithelium.
This dysplasia is part of a condition called cervical intraepithelial neoplasia (CIN). This condition has three degrees of severity: CIN I – Dysplasia in only lower 1/3 of epithelium, CIN II – Dysplasia in lower 2/3 of epithelium, and CIN III – Dysplasia in the whole epithelium. CIN is a precancerous lesion for cervical cancer. CIN III is the closest to becoming cancer while CIN I is the earliest stage. However, not all CIN III lesions become cancer – only 10% of them become cancerous. Because dysplasia is in the whole width of the epithelium in this slide it is classified as CIN III.
 
CIN is a precancerous lesion for cervical cancer. CIN III is the closest to becoming cancer while CIN I is the earliest stage. However, not all CIN III lesions become cancer – only 10% of them become cancerous. Because dysplasia is in the whole width of the epithelium in this slide it is classified as CIN III.
[[Category:Pathology 1 - Histopathology slides]]
[[Category:Pathology 1 - Histopathology slides]]