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34. Cervical intraepithelial neoplasia CIN III: Difference between revisions

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'''Description''':
'''Description''':


We can see two sections of a cervix. The top one is the best, so we’ll go with that.
We can see two sections of a cervix. The top one is the best, so we’ll go with that. On the bottom left corner can we see a very PAS-positive area. Upon closer inspection can we see that the PAS positive cells are stratified squamous cells. The other epithelium found in this section isn’t PAS-positive. This epithelial layer is also much thicker than the other.


On the bottom left corner can we see a very PAS-positive area. Upon closer inspection can we see that the PAS positive cells are stratified squamous cells.
The PAS-negative epithelium contains pleomorphic cells (they have different shapes and sizes). These cells are larger than the PAS-positive cells as well. We can also see some cells undergoing mitosis here. A special cell type with a white “ring” around an irregular nucleus can be seen.


The other epithelium found in this section isn’t PAS-positive. This epithelial layer is also much thicker than the other.
'''Diagnosis''': Cervical intraepithelial neoplasia CIN III[[File:CIN III dysplasia transition.png|thumb|This picture shows the abrupt change from healthy, PAS-positive epithelium to PAS-negative dysplasia.]]'''Causes''': <abbr>HPV</abbr> infection
 
The PAS-negative epithelium contains pleomorphic cells (they have different shapes and sizes). These cells are larger than the PAS-positive cells as well. We can also see some cells undergoing mitosis here.
 
A special cell type with a white “ring” around an irregular nucleus can be seen.
 
'''Diagnosis''': Cervical intraepithelial neoplasia CIN III[[File:CIN III dysplasia transition.png|thumb|This picture shows the abrupt change from healthy, PAS-positive epithelium to PAS-negative dysplasia.]]'''Causes''':
 
* <abbr>HPV</abbr> infection


'''Theory''':
'''Theory''':