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21. Central haemorrhagic necrosis: Difference between revisions

21. Central haemorrhagic necrosis (view source)

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If a patient already has nutmeg liver ''and'' develops acute left ventricular failure will there be a haemorrhagic necrosis around the central veins, called ''central haemorrhagic liver necrosis''. The necrosis occurs because of the hypoxia from the left ventricular failure, while the haemorrhage comes from the congestion from the right ventricular failure.
If a patient already has nutmeg liver ''and'' develops acute left ventricular failure will there be a haemorrhagic necrosis around the central veins, called ''central haemorrhagic liver necrosis''. The necrosis occurs because of the hypoxia from the left ventricular failure, while the haemorrhage comes from the congestion from the right ventricular failure.
''If you are having problems seeing the necrosis around the central veins (like many have), keep in mind what hepatocytes look like. They have large, round nuclei. The small nuclei around the central veins do not belong to hepatocytes, but to white blood cells. If you keep this in mind can you see that many hepatocytes here actually don’t have a nucleus, and are therefore necrotic. See the last picture.''
[[File:Central haemorrhagic necrosis of the liver - incipient periportal fibrosis.png|thumb|Incipient periportal fibrosis. The wavy stuff is the fibrosis.|left]]
[[File:Central haemorrhagic necrosis of the liver - incipient periportal fibrosis.png|thumb|Incipient periportal fibrosis. The wavy stuff is the fibrosis.|left]]
[[File:Central haemorrhagic necrosis of the liver - fatty degeneration.png|thumb|Fatty degeneration]]
[[File:Central haemorrhagic necrosis of the liver - fatty degeneration.png|thumb|Fatty degeneration]]
[[File:Central haemorrhagic necrosis of the liver - necrotic area.png|thumb|Central haemorrhagic necrosis.|left]]
[[File:Central haemorrhagic necrosis of the liver - necrotic area.png|thumb|Central haemorrhagic necrosis.|left]]
[[File:Central haemorrhagic necrosis of the liver - necrotic hepatocytes.png|thumb|If you are having problems seeing the necrosis around the central veins (like many have), keep in mind what hepatocytes look like. They have large, round nuclei. The small nuclei around the central veins do not belong to hepatocytes, but to white blood cells. If you keep this in mind can you see that many hepatocytes here actually don’t have a nucleus, and are therefore necrotic.]]
[[File:Central haemorrhagic necrosis of the liver - necrotic hepatocytes.png|thumb|Differentiatin between hepatocytes and leukocytes.]]
[[Category:Pathology 1 - Histopathology slides]]
[[Category:Pathology 1 - Histopathology slides]]