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20. DIC (fibrinthrombi in kidney) (fibrin stain): Difference between revisions

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'''Diagnosis''': DIC – phase 1
'''Diagnosis''': DIC – phase 1


'''Theory''':
'''Theory''': In phase I of disseminated intravascular coagulopathy (DIC), the thrombotic phase, will there be microthrombus and microembolism formation in every organ. In the kidney are the glomerular capillaries especially affected by this. Some tubules also appear to be fibrin-positive, however this is a ''false positive'' result. There is no fibrin inside the tubule cells.[[File:DIC in kidney - closer up.jpg|thumb|Closer up|left]]
 
In phase I of disseminated intravascular coagulopathy (DIC), the thrombotic phase, will there be microthrombus and microembolism formation in every organ. In the kidney are the glomerular capillaries especially affected by this.
 
Some tubules also appear to be fibrin-positive, however this is a ''false positive'' result. There is no fibrin inside the tubule cells.
[[File:DIC in kidney - closer up.jpg|thumb|Closer up|left]]
[[File:DIC in kidney - glomeruli.jpg|thumb|The glomeruli are clearly positive for fibrin.|275x275px]]
[[File:DIC in kidney - glomeruli.jpg|thumb|The glomeruli are clearly positive for fibrin.|275x275px]]
[[File:DIC in kidney - tubules.png|thumb|Some tubules also appear fibrin-positive, however they don’t contain fibrin.|left|262x262px]]
[[File:DIC in kidney - tubules.png|thumb|False positive tubules|left|262x262px]]
[[Category:Pathology 1 - Histopathology slides]]
[[Category:Pathology 1 - Histopathology slides]]