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(Created page with "'''Organ''': Heart '''Description''': A slice of the heart can be seen. Most notably the left ventricle is severely dilated. Note that the ventricular wall isn’t abnormally thick. '''Diagnosis''': Dilatative hypertrophy of the left ventricle '''Causes''': * Increased preload ** Aortic insufficiency ** Mitral insufficiency '''Theory''': This topic is best understood in tandem with preparation 17. When there is an increased preload, more blood volume will enter t...") |
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** Aortic insufficiency | ** Aortic insufficiency | ||
** Mitral insufficiency | ** Mitral insufficiency | ||
[[File:Dilative hypertrophic left ventricle prep.jpg|thumb|Dilative hypertrophic left ventricle prep]]'''Theory''': | |||
'''Theory''': | |||
This topic is best understood in tandem with preparation 17. | This topic is best understood in tandem with preparation 17. | ||
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# Increased preload causes dilatative hypertrophy | # Increased preload causes dilatative hypertrophy | ||
# The Laplace law states that increased dilation of the ventricle causes increased strain on the ventricular wall. This increased strain causes a decrease in contractility. | # The Laplace law states that increased dilation of the ventricle causes increased strain on the ventricular wall. This increased strain causes a decrease in contractility. | ||
# The decreased contractility eventually results in the ventricle not being able to compensate for failing heart, causing decompensation. | # The decreased contractility eventually results in the ventricle not being able to compensate for failing heart, causing decompensation. | ||
[[Category:Pathology 1 - Macropreparations]] | [[Category:Pathology 1 - Macropreparations]] |