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Necrotising soft tissue infection: Difference between revisions
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(Created page with "'''Necrotising soft tissue infections''' (NSTI) are necrotising bacterial infections of the soft tissues, which are life-threatening and must be treated surgically immediately. Depending on the affected soft tissue, this may be '''necrotising fasciitis, necrotising myositis,''' or '''necrotising cellulitis'''. It can progress rapidly and so early recognition is important. Treatment involves early broad-spectrum antibiotics and surgical debridement. Despite optimal therap...") |
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'''Necrotising soft tissue infections''' (NSTI) are necrotising bacterial infections of the soft tissues, which are life-threatening and must be treated surgically immediately. Depending on the affected soft tissue, this may be '''necrotising fasciitis, necrotising myositis,''' or '''necrotising cellulitis'''. It can progress rapidly and so early recognition is important. Treatment involves early broad-spectrum antibiotics and surgical debridement. Despite optimal therapy, the mortality is high. | <section begin="dermatology" />'''Necrotising soft tissue infections''' (NSTI) are necrotising bacterial infections of the soft tissues, which are life-threatening and must be treated surgically immediately. Depending on the affected soft tissue, this may be '''necrotising fasciitis, necrotising myositis,''' or '''necrotising cellulitis'''. It can progress rapidly and so early recognition is important. Treatment involves early broad-spectrum antibiotics and surgical debridement. Despite optimal therapy, the mortality is high. | ||
== Etiology == | == Etiology == | ||
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Antibiotic therapy must be broad-spectrum and cover gram-positives, gram-negatives, and anaerobes. Several antibiotics are needed, one of which should be [[clindamycin]], for its anti-toxin properties. | Antibiotic therapy must be broad-spectrum and cover gram-positives, gram-negatives, and anaerobes. Several antibiotics are needed, one of which should be [[clindamycin]], for its anti-toxin properties. | ||
In case of confirmed or suspected streptococcal infection, administration of [[IVIG]] is indicated as it reduces mortality.<noinclude>[[Category:Infectious disease]] | In case of confirmed or suspected streptococcal infection, administration of [[IVIG]] is indicated as it reduces mortality.<section end="dermatology" /><noinclude>[[Category:Infectious disease]] | ||
[[Category:Plastic surgery]]</noinclude> | [[Category:Plastic surgery]]</noinclude> | ||