5,421
edits
(Created page with "Several laboratory tests can be used to estimate the kidney function. These are important in the evaluation of chronic kidney disease (CKD) and acute kidney injury (AKI). The most common one is using the serum creatinine level to calculate the estimated glomerular filtration rate (eGFR). == Serum creatinine == Creatinine is a breakdown product of creatine phosphate following the creatine kinase reaction. It is eliminated by the kidneys by glome...") |
No edit summary |
||
Line 1: | Line 1: | ||
Several laboratory tests can be used to estimate the kidney function. These are important in the evaluation of [[chronic kidney disease]] (CKD) and [[acute kidney injury]] (AKI). The most common one is using the serum creatinine level to calculate the estimated [[glomerular filtration rate]] (eGFR). | <section begin="clinical biochemistry" />Several laboratory tests can be used to estimate the kidney function. These are important in the evaluation of [[chronic kidney disease]] (CKD) and [[acute kidney injury]] (AKI). The most common one is using the serum creatinine level to calculate the estimated [[glomerular filtration rate]] (eGFR). | ||
== Serum creatinine == | == Serum creatinine == | ||
Line 48: | Line 48: | ||
== Tubular function == | == Tubular function == | ||
There is no serum marker for tubular function. To evaluate function of the kidney tubules, one must examine the urine. Low urine osmolality, high urinary sodium concentration, and proteinuria are typical features of kidney tubule dysfunction or injury. This may reflect tubulointerstitial AKI or CKD. | There is no serum marker for tubular function. To evaluate function of the kidney tubules, one must examine the urine. Low urine osmolality, high urinary sodium concentration, and proteinuria are typical features of kidney tubule dysfunction or injury. This may reflect tubulointerstitial AKI or CKD. | ||
<section end="clinical biochemistry" /> | |||
== References == | == References == | ||
<references /> | <references /> | ||
[[Category:Laboratory Medicine]] | [[Category:Laboratory Medicine]] |