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Metabolic acidosis: Difference between revisions
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{{Infobox medical condition | <section begin="clinical biochemistry" />{{Infobox medical condition | ||
| name = Metabolic acidosis | | name = Metabolic acidosis | ||
| definition = A process decreasing pH due to metabolic process | | definition = A process decreasing pH due to metabolic process | ||
| Line 95: | Line 95: | ||
In case of acidosis, the body will compensate by hyperventilating. This decreases pCO2. It's important to evaluate pCO2 to determine whether respiratory compensation is effective or not. The pCO2 should be reduced to approximately [HCO3-] + 15. One may also subtract 7 from the pH and multiply by 100 to get the optimal pCO2 level. For example, if the pH is 7.23, the pCO2 should be 23 mmHg. If the pCO2 is not at the expected level, there is an impairment of the body's compensatory response to acidosis, or there may be a [[mixed acid-base disorder]]. | In case of acidosis, the body will compensate by hyperventilating. This decreases pCO2. It's important to evaluate pCO2 to determine whether respiratory compensation is effective or not. The pCO2 should be reduced to approximately [HCO3-] + 15. One may also subtract 7 from the pH and multiply by 100 to get the optimal pCO2 level. For example, if the pH is 7.23, the pCO2 should be 23 mmHg. If the pCO2 is not at the expected level, there is an impairment of the body's compensatory response to acidosis, or there may be a [[mixed acid-base disorder]]. | ||
<section end="clinical biochemistry" /> | |||
== Management == | == Management == | ||
As metabolic acidosis is not a disease of itself but rather a consequence, the underlying disease must be identified and treated. This will reverse the metabolic acidosis. | As metabolic acidosis is not a disease of itself but rather a consequence, the underlying disease must be identified and treated. This will reverse the metabolic acidosis. | ||