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Sodium: Difference between revisions
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<section begin="clinical biochemistry" />'''Sodium''' is an abundant electrolyte in the body, and sodium ion (Na+) is the dominant ion in the extracellular space. 65% of sodium is in the extracellular space. Abnormally low or high sodium ([[hyponatraemia]] and [[hypernatraemia]], respectively), are common but potentially lethal disorders in the worst case.<section end="clinical biochemistry" /> | <section begin="clinical biochemistry" />'''Sodium''' is an abundant electrolyte in the body, and sodium ion (Na+) is the dominant ion in the extracellular space. 65% of sodium is in the extracellular space. Abnormally low or high sodium ([[hyponatraemia]] and [[hypernatraemia]], respectively), are common but potentially lethal disorders in the worst case.<section end="clinical biochemistry" /> | ||
<section begin="clinical biochemistry" /> | <section begin="clinical biochemistry" /> | ||
== Sodium in the body == | |||
70% of sodium in the body is free, not bound to any molecules. | |||
The remaining 30% is not free but rather bound to large organic molecules in bone, cartilage, and connective tissue. | |||
== Sodium regulation == | == Sodium regulation == | ||
The level of sodium in the body is regulated by the [[renin-angiotensin-aldosterone system]] (RAAS) and by [[anti-diuretic hormone]] (ADH). <section end="clinical biochemistry" /> | The level of sodium in the body is regulated by the [[renin-angiotensin-aldosterone system]] (RAAS) and by [[anti-diuretic hormone]] (ADH). <section end="clinical biochemistry" /> | ||