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31. Pathogenesis and clinicopathology of tuberculosis: Difference between revisions
31. Pathogenesis and clinicopathology of tuberculosis (view source)
Revision as of 21:49, 25 January 2024
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(Created page with "Tuberculosis is a chronic granulomatous disease which usually involves the lungs, but may affect other organs as well, like the kidneys. The centre of the tubercular granulomas typically undergo caseous necrosis. === Epidemiology === Apparently, every third human is infected with tuberculosis. In 2016 there were 10,4 million new cases! And 1,5 million deaths due to the disease the same year. We in Europe are very lucky to live in an almost tuberculosis-free reality. Al...") |
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=== Microbiology === | === Microbiology === | ||
Tuberculosis is caused by bacterium in the Mycobacterium Tuberculosis family. The mycobacteria are obligate aerobe bacteria, which means that they are dependent on oxygen to live. These bacteria are also capable of living both inside and outside cells and reproduce, therefore making them ''facultative'' intracellular pathogens. They proliferate slowly. | Tuberculosis is caused by bacterium in the Mycobacterium Tuberculosis family. The mycobacteria are obligate aerobe bacteria, which means that they are dependent on oxygen to live. These bacteria are also capable of living both inside and outside cells and reproduce, therefore making them ''facultative'' intracellular pathogens. They proliferate slowly. Mycobacteriae are stained with Ziehl–Neelsen staining, also called acid-fast staining. | ||
There are three different types: | There are three different types: | ||