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Precancerous states of the GI tract: Difference between revisions
Precancerous states of the GI tract (view source)
Revision as of 20:56, 26 November 2023
, 26 November 2023→Oral leukoplakia and erythroplakia
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Barrett oesophagus with high-grade dysplasia is treated with mucosectomy (endoscopic resection) or endoscopic ablation, same as T1A oesophageal cancer. No dysplasia or low-grade dysplasia may be managed either with regular surveillance or endoscopic removal. | Barrett oesophagus with high-grade dysplasia is treated with mucosectomy (endoscopic resection) or endoscopic ablation, same as T1A oesophageal cancer. No dysplasia or low-grade dysplasia may be managed either with regular surveillance or endoscopic removal. | ||
== Oral leukoplakia and erythroplakia == | <section begin="leukoplakia and erythroplakia" />== Oral leukoplakia and erythroplakia == | ||
Leukoplakia is an unbrushable white lesion, while the erythoplakias are fiery red. They are associated with increased risk of cancer and have normally no symptoms. The risk factors for leuko- and erythroplakias are [[smoking]], chewing tobacco and excessive [[alcohol]] intake. | Leukoplakia is an unbrushable white lesion, while the erythoplakias are fiery red. They are associated with increased risk of cancer and have normally no symptoms. The risk factors for leuko- and erythroplakias are [[smoking]], chewing tobacco and excessive [[alcohol]] intake. | ||
The risks of progression into invasive squamous cell carcinoma is 3-25% with leukoplakia, and more than 50% with erythroplakia. It’s important to distinguish them from benign oral lesions like oral candidiasis. | The risks of progression into invasive squamous cell carcinoma is 3-25% with leukoplakia, and more than 50% with erythroplakia. It’s important to distinguish them from benign oral lesions like oral candidiasis. | ||
These precancerous lesions should be surgically removed, or alternatively, regularly surveyed. Avoiding risk factors is important to prevent recurrence or progression. | These precancerous lesions should be surgically removed, or alternatively, regularly surveyed. Avoiding risk factors is important to prevent recurrence or progression.<section end="leukoplakia and erythroplakia" /> | ||
== Familial adenomatous polyposis == | == Familial adenomatous polyposis == | ||