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(Created page with "'''Acute myocardial infarction''' (AMI), sometimes called a '''heart attack''', is a life-threatening condition caused by ischaemia of the myocardium. == Pathomechanism == AMI occurs when a coronary atherosclerotic plaque ruptures, exposing the highly thrombogenic subendothelial matrix of the plaque to the blood. The coagulation system is activated, resulting in a thrombus growing on the ruptured plaque and obstructing the blood flow. When the...") |
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The process described above refers to the most common type of infarction, the so-called ''type 1 infarct''. Other types of infarcts also exist, most notably type 2 infarcts. In type 2 infarcts there is an increased oxygen demand and/or decreased oxygen supply to the myocardium which is not due to coronary artery thrombosis. This can be due to coronary artery spasm, embolus, [[Tachyarrhythmia|tachyarrhythmias]], [[anaemia]], [[respiratory failure]], [[hypertension]], [[hypotension]], etc. Up to 28% of patients with myocardial infarction don’t have significant [[Ischaemic heart disease|coronary artery disease]] and so their underlying cause must be something else, presumably a type 2 infarction. | The process described above refers to the most common type of infarction, the so-called ''type 1 infarct''. Other types of infarcts also exist, most notably type 2 infarcts. In type 2 infarcts there is an increased oxygen demand and/or decreased oxygen supply to the myocardium which is not due to coronary artery thrombosis. This can be due to coronary artery spasm, embolus, [[Tachyarrhythmia|tachyarrhythmias]], [[anaemia]], [[respiratory failure]], [[hypertension]], [[hypotension]], etc. Up to 28% of patients with myocardial infarction don’t have significant [[Ischaemic heart disease|coronary artery disease]] and so their underlying cause must be something else, presumably a type 2 infarction. | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
[[Category:Internal Medicine (POTE course)]] |