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Kidney transplant rejection: Difference between revisions
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(Created page with "'''Kidney transplant rejection''' is a serious complication following kidney transplantion which may lead to graft loss. We distinguish several types. == Early complications following kidney transplantation == Acute renal allograft rejection is a severe complication of kidney transplantation. Thanks to modern immunosuppressant drugs and induction regimens there has been a considerable reduction in acute rejections in the past decades. Acute rejection is defined as an ac...") |
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'''Kidney transplant rejection''' is a serious complication following kidney transplantion which may lead to graft loss. We distinguish several types. | '''Kidney transplant rejection''' is a serious complication following [[kidney transplantion]] which may lead to graft loss. We distinguish several types. | ||
== Early complications following kidney transplantation == | == Early complications following kidney transplantation == | ||
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=== Treatment === | === Treatment === | ||
There is no effective therapy for late rejection, and all patients inevitably progress to [[end-stage kidney disease]]. However, calcineurin inhibitors like [[tacrolimus]] are nephrotoxic, and so reduction of tacrolimus is often tried in an attempt to slow the progression. Any concomitant kidney disease should be treated, and renal risk factors should be reduced. | There is no effective therapy for late rejection, and all patients inevitably progress to [[end-stage kidney disease]]. However, calcineurin inhibitors like [[tacrolimus]] are nephrotoxic, and so reduction of tacrolimus is often tried in an attempt to slow the progression. Any concomitant kidney disease should be treated, and renal risk factors should be reduced. | ||
<noinclude>[[Category:Transplant surgery]]</noinclude> | <noinclude> | ||
[[Category:Transplant surgery]] | |||
</noinclude> | |||