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Aortic aneurysms are problematic because they can rupture, which kills most of affected people within minutes or hours, and because they can compress other structures. These aneurysms typically grow slowly, but the risk of rupture and compression increase with the size. | Aortic aneurysms are problematic because they can rupture, which kills most of affected people within minutes or hours, and because they can compress other structures. These aneurysms typically grow slowly, but the risk of rupture and compression increase with the size. | ||
==Pathology== | |||
<noinclude>[[Category:Vascular surgery]] | Degeneration of elastic and collagen fibres, as well as [[atherosclerosis]], causes the formation of the aneurysm. Degeneration occurs due to mechanical stress due to [[hypertension]] and due to activation of proteases like [[collagenase]], [[elastase]], [[matrix metalloproteinase]], and [[plasmin]].<noinclude>[[Category:Vascular surgery]] | ||
</noinclude> | </noinclude> |