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Peptic ulcer disease: Difference between revisions

Peptic ulcer disease (view source)

Revision as of 20:55, 10 September 2023

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These ulcers can cause pain or [[Gastrointestinal bleeding|GI bleeding]].
These ulcers can cause pain or [[Gastrointestinal bleeding|GI bleeding]].


== Etiology ==
In addition to H. pylori and NSAIDs, there are multiple other “supportive” risk factors. These include smoking, alcohol, steroid use, and stress. Severe stress like trauma, burns and surgery may predispose to PUD. These ulcers sometimes have special names: ''Curling-ulcus'' after severe burn injury, and ''Cushing-ulcus'' after CNS injury.
In addition to H. pylori and NSAIDs, there are multiple other “supportive” risk factors. These include smoking, alcohol, steroid use, and stress. Severe stress like trauma, burns and surgery may predispose to PUD. These ulcers sometimes have special names: ''Curling-ulcus'' after severe burn injury, and ''Cushing-ulcus'' after CNS injury.
The most important risk factors for ulcer bleeding are:
* NSAID and aspirin use
* H. pylori infection
* Alcohol
* Anticoagulants and antiplatelets


== Pathology ==
== Pathology ==