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Primary biliary cholangitis: Difference between revisions
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(Created page with "Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune chronic liver disease characterised by progressive destruction of intralobular bile ducts leading to intrahepatic cholestasis. Eventually, cirrhosis develops. It almost exclusively affects middle-aged women and is associated with other autoimmune disorders. == Clinical features == PBC may present asymptomatically (only abnormal laboratory parameters) as it remains asympto...") |
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Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune chronic liver disease characterised by progressive destruction of intralobular bile ducts leading to intrahepatic cholestasis. Eventually, cirrhosis develops. | '''Primary biliary cholangitis''' (PBC), previously known as '''primary biliary cirrhosis''', is an autoimmune chronic liver disease characterised by progressive destruction of intralobular bile ducts leading to intrahepatic cholestasis. Eventually, cirrhosis develops. | ||
It almost exclusively affects middle-aged women and is associated with other autoimmune disorders. | It almost exclusively affects middle-aged women and is associated with other autoimmune disorders. | ||