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== Drugs that inhibit formation of eicosanoids == | == Drugs that inhibit formation of eicosanoids == | ||
NSAIDs inhibit COX-1 and/or COX-2, depending on the type of NSAID. | NSAIDs inhibit COX-1 and/or COX-2, depending on the type of NSAID. NSAIDs are covered in another topic. | ||
Glucocorticoids increase the synthesis of lipocortin, a protein which inhibits phospholipase A2. | Glucocorticoids increase the synthesis of lipocortin, a protein which inhibits phospholipase A2. Glucocorticoids are covered in another topic. | ||
== Drugs which relax smooth muscle == | == Drugs which relax smooth muscle (spasmolytics) == | ||
=== Compounds === | === Compounds === | ||
* No clinical use | |||
** Papaverine | |||
** Drotaverine | |||
* Metamizole | |||
* Butylscopolamine | |||
* Bencyclane | |||
Many drugs act on smooth muscle, including eicosanoids, however we reserve the name spasmolytic drugs for drugs that prevent spasms of the smooth muscles in the GI tract or genitourinary tract. | Many drugs act on smooth muscle, including eicosanoids, however we reserve the name spasmolytic drugs for drugs that prevent spasms of the smooth muscles in the GI tract or genitourinary tract. |