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(Created page with "Schizophrenia is a disorder characterised by chronic or recurrent psychosis, often with impairments in social and occupational functioning. It's a common disorder in psychiatry and a major cause of disability worldwide. The prevalence is approximately 1%, and it affects men slightly more often than women. The name comes from the Greek words "to split" (schizo) and "mind" (fren). == Etiology == The etiology and pathogenesis of schizophrenia is unknown, but it's bel...") |
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== Etiology == | == Etiology == | ||
The etiology and pathogenesis of schizophrenia is unknown, but it's believed that it may be a syndrome of multiple diseases with similar signs and symptoms, rather than a single disease. It's known that a complex interaction between genetic factors and environmental factors are involved. There is significant [[concordance]], showing a significant genetic component. Cigarette smoking and cannabis are known environmental risk factors, as are childhood adversities and immigration. | The etiology and pathogenesis of schizophrenia is unknown, but it's believed that it may be a syndrome of multiple diseases with similar signs and symptoms, rather than a single disease. It's known that a complex interaction between genetic factors and environmental factors are involved. There is significant [[concordance]], showing a significant genetic component. | ||
Cigarette smoking and cannabis are known environmental risk factors, as are childhood adversities and immigration. Those who have a valine-valine polymorphism in the COMT enzyme are at especially high risk for schizophrenia if they use cannabis. | |||
== Clinical features == | == Clinical features == |