Nikolas
Created page with "'''Thrombotic thrombocytic purpura''' (TTP) is a thrombotic microangiopathy characterised by thrombocytopaenia, microangiopathic haemolysis, neurological abnormalities, renal abnormalities, and low levels of a protein called ADAMTS-13. It is primarily seen in adults and is typically caused by acquired autoantibodies against the enzyme cleaving von Willebrand factor, vWF, known as ADAMTS13. Deficiency of ADAMTS13 leads to excess vWF which in turn leads to mic..."
