Nikolas
Created page with "<section begin="dermatology" />* In middle-aged, elderly * Deadly without treatment * Pathomechanism ** Autoantibodies against desmosomes ** Acantholysis – loss of cell-cell adhesion * Clinical features ** Painful, flaccid, intraepidermal (superficial) blisters ** -> lesions rupture ** -> erosions and crusts ** -> re-epithelialization with hyperpigmentation but no scarring ** No pruritus ** Lesions often begin in oral mucosa then to body parts exposed to pressure * Dia..."
