Nikolas
Created page with "== Etiology == The basic mechanism behind 1DM is a destruction of pancreatic β-cells. The other endocrine functions of the pancreas are usually maintained. The exact cause of the destruction isn’t completely understood. There are both genetic and environmental factors. Genetic factors: Concordance between identical twins is only 40% and between parent and child only 5%. This indicates that genetic factors play only a minor role. Certain types of HLA, especially HLA-D..."